Results 131 to 140 of about 967,825 (378)
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
Local Codes with Addition Based Repair [PDF]
arXiv, 2015 We consider the complexities of repair algorithms for locally repairable codes and propose a class of codes that repair single node failures using addition operations only, or codes with addition based repair. We construct two families of codes with addition based repair.
arxiv
DNA damage repair in ovarian cancer: unlocking the heterogeneity
Journal of Ovarian Research, 2018 Treatment for advanced ovarian cancer is rarely curative; three quarters of patients with advanced disease relapse and ultimately die with resistant disease.
Mary Ellen Gee +3 more
doaj +1 more source
The base excision repair process: comparison between higher and lower eukaryotes
Cellular and Molecular Life Sciences, 2021 N. Hindi, Noha Elsakrmy, D. Ramotar
semanticscholar +1 more source
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Molecular Oncology, Volume 19, Issue 4, Page 1029-1053, April 2025.Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler +12 more
wiley +1 more source
Automated Image Processing for the Analysis of DNA Repair Dynamics [PDF]
arXiv, 2011 The efficient repair of cellular DNA is essential for the maintenance and inheritance of genomic information. In order to cope with the high frequency of spontaneous and induced DNA damage, a multitude of repair mechanisms have evolved. These are enabled by a wide range of protein factors specifically recognizing different types of lesions and finally ...
arxiv
Molecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
MR-RePair: Grammar Compression based on Maximal Repeats [PDF]
arXiv, 2018 We analyze the grammar generation algorithm of the RePair compression algorithm and show the relation between a grammar generated by RePair and maximal repeats. We reveal that RePair replaces step by step the most frequent pairs within the corresponding most frequent maximal repeats.
arxiv
Base Excision Repair Gene Polymorphisms and Wilms Tumor Susceptibility
EBioMedicine, 2018 Base excision repair (BER) is the main mechanism to repair endogenous DNA lesions caused by reactive oxygen species. BER deficiency is linked with cancer susceptibility and premature aging.
Jinhong Zhu +6 more
doaj