Fidelity of Uracil-initiated Base Excision DNA Repair in DNA Polymerase β-Proficient and -Deficient Mouse Embryonic Fibroblast Cell Extracts [PDF]
, 2001 Samuel Bennett +2 more
openalex +1 more source
NAD+-mediated regulation of mammalian base excision repair.
DNA Repair, 2020 Kate M. Saville +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Excessive base excision repair of 5-hydroxymethyluracil from DNA induces apoptosis in Chinese hamster V79 cells containing mutant p53 [PDF]
, 2001 L.-J. Mi
openalex +1 more source
Molecular Oncology, Volume 19, Issue 4, Page 1075-1091, April 2025.Pancreatic ductal adenocarcinoma patient‐derived xenografts (PDAC‐PDXs) engrafted orthotopically in the pancreas of immunodeficient mice retain the main genetic and histopathological characteristics of the original human tumors. A 294 stroma gene signature differentiates between PDAC‐PDXs that are responsive to gemcitabine plus nab‐paclitaxel versus ...
Alessia Anastasia +13 more
wiley +1 more source
A method for detecting abasic sites in living cells: Age-dependent changes in base excision repair
, 2000 Hani Atamna, Ivana Cheung, Bruce N. Ames
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
The Role of Poly(ADP-ribose) Polymerase 1 in Nuclear and Mitochondrial Base Excision Repair. [PDF]
Biomolecules, 2023 Herrmann GK, Yin YW.
europepmc +1 more source
Counteracting spontaneous transformation via overexpression of rate-limiting DNA base excision repair enzymes [PDF]
, 2001 openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source