Results 91 to 100 of about 64,874 (247)
Introdução. Este artigo é decorrente de uma macropesquisa, financiada pela Chamada Universal do Conselho Nacional de Desenvolvimento Científico e Tecnológico.
Heloisa Beatriz Silva Dillio +1 more
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
PRÁTICAS DE LINGUAGEM NA BASE NACIONAL COMUM CURRICULAR
O objetivo deste estudo é discutir sobre como a Base Nacional Comum Curricular (BNCC) para o Ensino Médio propõe a integração das práticas de linguagem e sobre como essas normatizações são apresentadas nas propostas de ensino de autores como: Avelar ...
Thiago de Sousa Amorim +2 more
doaj +1 more source
Este artigo traz à discussão duas perspectivas de análise discursiva que propomos como complementares e interdependentes: a visão biopolítica e o olhar semântico-polifônico.
Rosa, Geraldo Antonio da
doaj
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Este artigo investiga como guias, plataformas e programas digitais articulados à Base Nacional Comum Curricular (BNCC) operam como estratégias de prescrição da prática docente, produzindo sentidos de qualidade e tecnologia na forma de uma “prescrição ...
Ferreira, Lhays Marinho da Conceição
doaj
Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus +2 more
wiley +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source

