Results 81 to 90 of about 71,553 (287)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

ANÁLISE LINGUÍSTICA/SEMIÓTICA NA BASE NACIONAL COMUM CURRICULAR

, 2023
<p><strong>Resumo: </strong>A Base Nacional Comum Curricular – BNCC (2018), quanto ao ensino de língua portuguesa, procura estabelecer um diálogo com os documentos curriculares produzidos nas últimas décadas e, assim, passa a assumir ...
Cleciano de Souza Silva
core   +1 more source

An approach to the Urgencies and Emergencies Medicine

Medisan, 2018
A study on the development of the Urgencies and Emergencies Medicine, its main concepts and peculiarities is carried out. The current pattern of the SIUM  in Cuba is approached, which has been the solution to the severely-ill patient and it has allowed ...
Jorge Luis Sánchez Guillaume
doaj  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Base Nacional Comum Curricular: a história disputada em duas versões

, 2019
Este trabalho pretende apresentar os resultados finais da pesquisa de Iniciação Científica intitulada “Base Nacional Comum: representações e desdobramentos”, sob orientação da Prof.ª Dr.ª Margaria Dias.
Silva, Matheus Oliveira
core   +1 more source

O ENSINO DO TEATRO NA BASE NACIONAL COMUM CURRICULAR

, 2021
Neste artigo analisa-se a proposta para o ensino do Teatro apresentada no documento normativo Base Nacional Comum Curricular – BNCC, homologada nos sistemas de ensino do Brasil em maio de 2018.
Wisnievski, Roberta Jorge da Silva, Rosseto, Robson   +1 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A BASE NACIONAL COMUM CURRICULAR E OS SUJEITOS QUE DIRECIONAM A POLÍTICA EDUCACIONAL BRASILEIRA

, 2019
The article enquires into, and maps the subjects that have influenced the construction and implementation of the National Curricular Common Base (BNCC) through the insertion of private proposals in the process. The BNCC is a demand of the Law of National
Caetano, Maria Raquel
core   +2 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source