Probing Hybridization parameters from microarray experiments: nearest neighbor model and beyond [PDF]
, 2012 In this article it is shown how optimized and dedicated microarray experiments can be used to study the thermodynamics of DNA hybridization for a large number of different conformations in a highly parallel fashion.
Carlon, Enrico +3 more
core +3 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Screening of anomalies in a double-stranded DNA via global electrical measurements
AIP AdvancesWe conduct two-terminal charge transport calculations to detect biological defects in three types of DNA sequences: periodic, quasi-periodic and random.
Sourav Kundu
doaj +1 more source
Dependence of nucleosome mechanical stability on DNA mismatches
eLifeThe organization of nucleosomes into chromatin and their accessibility are shaped by local DNA mechanics. Conversely, nucleosome positions shape genetic variations, which may originate from mismatches during replication and chemical modification of DNA ...
Thuy TM Ngo +5 more
doaj +1 more source
Mismatch repair in recombination of bacteriophage T4
Biomolecular Concepts, 2012 The review focuses on the mechanism of mismatch repair in bacteriophage T4. It was first observed in T4 as an extra recombination mechanism, which contributed to the general recombination only when particular rII mutations were used as genetic markers ...
Shcherbakov Victor P.
doaj +1 more source
DNA Polymerase Inhibition by High Kinetic Stability of T-HgII-T Base Pairs
CHIMIA, 2017 A fluorescent surrogate of thymidine called DMAT was used for the first fluorescence-based study of HgII binding to discrete T-T sites in duplex DNA.
Olivia P. Schmidt
doaj +1 more source
Population genetic structure of Marbled Rockfish, Sebastiscus marmoratus (Cuvier, 1829), in the northwestern Pacific Ocean [PDF]
ZooKeys, 2019 Sebastiscus marmoratus is an ovoviviparous fish widely distributed in the northwestern Pacific. To examine the gene flow and test larval dispersal strategy of S.
Lu Liu +6 more
doaj +3 more sources
DNA nanotechnology: understanding and optimisation through simulation
, 2014 DNA nanotechnology promises to provide controllable self-assembly on the nanoscale, allowing for the design of static structures, dynamic machines and computational architectures.
Ouldridge, Thomas E.
core +1 more source
Stereochemical control of the DNA binding affinity, sequence specificity, and orientation preference of chiral hairpin polyamides in the minor groove [PDF]
, 1998 Three-ring polyamides containing pyrrole (Py) and imidazole (Im) amino acids covalently coupled by γ-aminobutyric acid (γ) form six-ring hairpins that recognize five-base-pair sequences in the minor groove of DNA.
Baird, Eldon E. +2 more
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source