Results 41 to 50 of about 41,346 (265)
Population genetic structure of Marbled Rockfish, Sebastiscus marmoratus (Cuvier, 1829), in the northwestern Pacific Ocean [PDF]
ZooKeys, 2019 Sebastiscus marmoratus is an ovoviviparous fish widely distributed in the northwestern Pacific. To examine the gene flow and test larval dispersal strategy of S.
Lu Liu +6 more
doaj +3 more sources
Influence of pH on the conformation and stability of mismatch base-pairs in DNA
Journal of Molecular Biology, 1990 A series of self-complementary dodecanucleotide duplexes containing two symmetrically disposed mismatches have been studied by pH-dependent, ultraviolet light melting techniques. The results indicate that A.C, and C.C mismatches are strongly stabilized by protonation and that the degree of stabilization of the A.C mismatch depends greatly on the ...
Brown, T +3 more
openaire +3 more sources
Highly sensitive and selective mercury sensor based on mismatched base pairing with dioxT [PDF]
Chemical Communications, 2019 A highly selective and sensitive sensor for mercury was designed based on a new fluorescent nucleobase, dioxT.
Ji Hoon Han +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Screening of anomalies in a double-stranded DNA via global electrical measurements
AIP AdvancesWe conduct two-terminal charge transport calculations to detect biological defects in three types of DNA sequences: periodic, quasi-periodic and random.
Sourav Kundu
doaj +1 more source
Mismatch repair in recombination of bacteriophage T4
Biomolecular Concepts, 2012 The review focuses on the mechanism of mismatch repair in bacteriophage T4. It was first observed in T4 as an extra recombination mechanism, which contributed to the general recombination only when particular rII mutations were used as genetic markers ...
Shcherbakov Victor P.
doaj +1 more source
Structures of mismatched base pairs in DNA and their recognition by the Escherichia coli mismatch repair system. [PDF]
The EMBO Journal, 1986 The Escherichia coli mismatch repair system does not recognize and/or repair all mismatched base pairs with equal efficiency: whereas transition mismatches (G X T and A X C) are well repaired, the repair of some transversion mismatches (e.g. A X G or C X T) appears to depend on their position in heteroduplex DNA of phage lambda.
G V, Fazakerley +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens
Nature CommunicationsCytosine base editors enable programmable and efficient genome editing using an intermediate featuring a U•G mismatch across from a DNA nick. This intermediate facilitates two major outcomes, C•G to T•A and C•G to G•C point mutations, and it is not ...
Sifeng Gu +5 more
doaj +1 more source
BioTechniques, 1997 A rapid, robust and widely applicable mutation detection scheme not requiring radioactivity or gel-based detection is introduced. It is a single-tube, competitive oligonucleotide single-base extension (COSBE) reaction using a pair of primers with the 3 ...
G. Scott Higgins +2 more
doaj +1 more source