Results 71 to 80 of about 40,087 (166)

SOPRA: Scaffolding algorithm for paired reads via statistical optimization

BMC Bioinformatics, 2010
Background High throughput sequencing (HTS) platforms produce gigabases of short read (
Michael Todd P, Dayarian Adel, Sengupta Anirvan M   +2 more
doaj   +1 more source

Localized Surface Plasmon Resonance Optical Biosensor for Simple Detection of Deoxyribonucleic Acid Mismatches

Advanced Photonics Research
Optical biosensors are optical technologies that evaluate changes in the refractive index as they monitor non‐covalent molecular interactions in real time.
Masixole Yvonne Lugongolo, Saturnin Ombinda‐Lemboumba, Lerato Hlekelele, Nontsikelelo Nyokana, Patience Mthunzi‐Kufa   +4 more
doaj   +1 more source

ARMSprimer3: An open-source primer design Python program for amplification refractory mutation system PCR (ARMS-PCR)

Journal of Pathology Informatics
Single nucleotide polymorphisms (SNPs) are DNA sequence variations of a single base pair. They are the underlying mechanism of most human genetic variation and etiology of many heritable human diseases.
Jingwen Guo, Jeremy Grojean, Huazhang Guo   +2 more
doaj   +1 more source

Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling

Nature Communications
The ability to analyze whether DNA contains lesions is essential in identifying mutagenic substances. Currently, the detection of single-stranded DNA breaks (SSBs) lacks precision.
Leonie Wenson, Johan Heldin, Marcel Martin, Yücel Erbilgin, Barış Salman, Anders Sundqvist, Wesley Schaal, Friederike A. Sandbaumhüter, Erik T. Jansson, Xingqi Chen, Anton Davidsson, Bo Stenerlöw, Jaime A. Espinoza, Mikael Lindström, Johan Lennartsson, Ola Spjuth, Ola Söderberg   +16 more
doaj   +1 more source

Amplified single base-pair mismatch detection via aggregation of exonuclease-sheared gold nanoparticles. [PDF]

Anal Chem, 2014
Wu S, Liang P, Yu H, Xu X, Liu Y, Lou X, Xiao Y.   +6 more
europepmc   +1 more source

Peptide Nucleic Acid Clamp‐Assisted Photothermal Multiplexed Digital PCR for Identifying SARS‐CoV‐2 Variants of Concern

Advanced Science
The unprecedented demand for variants diagnosis in response to the COVID‐19 epidemic has brought the spotlight onto rapid and accurate detection assays for single nucleotide polymorphisms (SNPs) at multiple locations.
Lexiang Zhang, Rokshana Parvin, Siyue Lin, Mingshuo Chen, Ruixuan Zheng, Qihui Fan, Fangfu Ye   +6 more
doaj   +1 more source

Pyrimidine · pyrimidine base-pair mismatches in DNA

Journal of Molecular Biology, 1988
Michael Kouchakdjian, Benjamin F.L. Li, Peter F. Swann, Dinshaw J. Patel   +3 more
openaire   +1 more source

Structural studies of DNA fragments with base pair mismatches [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 1987
O. Kennard, W. N. Hunter
openaire   +1 more source

Understanding the Fidelity and Specificity of DNA Polymerase I. [PDF]

ACS Omega
Miller BR, Yeager AV, Collins JA, Beane A, Blake A, Tate E, Parish CA, Wu EY.   +7 more
europepmc   +1 more source

HOOKSNIP: A BROWSER TOOL FOR DESIGNING ALLELE-SPECIFIC PCR PRIMERS IN HOOKWORM. [PDF]

J Parasitol
Jackson CA, Hawdon JM, O'Halloran DM.
europepmc   +1 more source