Results 91 to 100 of about 342,669 (235)
Defects Can Increase the Melting Temperature of DNA-Nanoparticle Assemblies
, 2007 DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable ...
Harris, Nolan C., Kiang, Ching-Hwa
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DNA with Artificial Base Pairs
CHIMIA, 2005 The introduction of a single base pair with the electronically complementary base surrogates phenyl- (P) and pentafluorophenyl-deoxyriboside (F5) into DNA oligonucleotides leads to a strong decrease in duplex stability. Longer stretches with alternating P-F5 pairs can lead to duplexes with increased stability as compared to their counterparts
Gérald Mathis, Jürg Hunziker
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Improved Cycle Sequencing of GC-Rich Templates by a Combination of Nucleotide Analogs
BioTechniques, 2000 A common problem in automated DNA sequencing when applying the Sanger chain termination method is ambiguous base calling caused by band compressions.
Michael Motz +2 more
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On the Doubly hydrogen bonded dimer of 7-azaindole (0.1 M) as a model for DNA base pairs in acetonitrile solutions at rt [PDF]
, 2008 Multiple H-bonded base-pairing as a fundamental element of DNA structure was first described by Watson and Crick using stable keto tautomer forms. In their analysis, they considered the possibility of mutations via tautomeric proton transfer shifts ...
Javier Catalan
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Stable stem enabled Shannon entropies distinguish non-coding RNAs from random backgrounds
BMC Bioinformatics, 2012 Background The computational identification of RNAs in genomic sequences requires the identification of signals of RNA sequences. Shannon base pairing entropy is an indicator for RNA secondary structure fold certainty in detection of structural, non ...
Wang Yingfeng +6 more
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Orthogonal Base Pairs Continue to Evolve [PDF]
Chemistry & Biology, 2004 Recent developments in the design and construction of unusual analogs of the natural nucleic acid bases have reached a milestone with the report (in this issue of Chemistry & Biology) of a new orthogonal base pair that allows site-specific introduction of a photo-crosslinkable modified base into an RNA molecule by T7 RNA polymerase-mediated ...
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Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain [PDF]
, 2010 Divalent cations are important in the folding and stabilization of complex RNA structures. The adenine-sensing riboswitch controls the expression of mRNAs for proteins involved in purine metabolism by directly sensing intracellular adenine levels ...
Noeske, Jonas +2 more
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, 2022 In dieser Masterarbeit untersuchen wir Pairings auf elliptischen Kurven, deren Anwendung in der Kryptographie und deren Berechnung. Pairings sind bestimmte bilineare Funktionen zwischen Gruppen, wobei wir solche Abbildungen insbesondere für die Gruppe der Punkte elliptischer Kurven finden können. Beide diese Begriffe werden in dieser Arbeit eingeführt.
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Capturing alternative secondary structures of RNA by decomposition of base-pairing probabilities
BMC Bioinformatics, 2018 Background It is known that functional RNAs often switch their functions by forming different secondary structures. Popular tools for RNA secondary structures prediction, however, predict the single ‘best’ structures, and do not produce alternative ...
Taichi Hagio +4 more
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Can re-entrance be observed in force induced transitions?
, 2009 A large conformational change in the reaction co-ordinate and the role of the solvent in the formation of base-pairing are combined to settle a long standing issue {\it i.e.} prediction of re-entrance in the force induced transition of DNA.
Bhattacharjee S. M. +11 more
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