Results 11 to 20 of about 2,954,117 (341)

Unzipping of DNA with correlated base sequence [PDF]

open access: yesPhysical Review E, 2004
We consider force-induced unzipping transition for a heterogeneous DNA model with a correlated base-sequence. Both finite-range and long-range correlated situations are considered. It is shown that finite-range correlations increase stability of DNA with respect to the external unzipping force. Due to long-range correlations the number of unzipped base-
Allahverdyan, A.   +3 more
openaire   +7 more sources

Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity

open access: yesMolecular Therapy: Nucleic Acids, 2023
Double-stranded DNA-specific cytidine deaminase (DddA) base editors hold great promise for applications in bio-medical research, medicine, and biotechnology.
Kai Cheng   +14 more
doaj   +1 more source

Enteropathogenic Escherichia coli O157 Strains from Brazil

open access: yesEmerging Infectious Diseases, 2003
We describe two serogroup O157 Escherichia coli strains from Brazilian infants with diarrhea. A variety of assays indicate that these strains belong to the enteropathogenic, not the enterohemorrhagic, pathotype.
T. Eric Blank   +5 more
doaj   +1 more source

Sequence dependency of canonical base pair opening in the DNA double helix. [PDF]

open access: yesPLoS Computational Biology, 2017
The flipping-out of a DNA base from the double helical structure is a key step of many cellular processes, such as DNA replication, modification and repair.
Viveca Lindahl   +2 more
doaj   +1 more source

Sequence-Based Linkage Analysis [PDF]

open access: yesThe American Journal of Human Genetics, 2004
The rapid decrease in the cost of DNA sequencing will enable its use for novel applications. Here, we investigate the use of DNA sequencing for simultaneous discovery and genotyping of polymorphisms in family linkage studies. In the proposed approach, short contiguous segments of genomic DNA, regularly spaced across the genome, are resequenced in each ...
Furman, Itay   +6 more
openaire   +2 more sources

Knowledge Modeling in Troubleshooting

open access: yesИнженерные технологии и системы, 2021
Introduction. The article describes the approach to solving the problem of complex technical system troubleshooting based on expert knowledge modeling.
Valeriy P. Dimitrov   +2 more
doaj   +1 more source

DEPASCALISATION OF SMARANDACHE PASCAL DERIVED SEQUENCES AND BACKWARD EXTENDED FIBONACCI SEQUENCE [PDF]

open access: yes, 2001
We call the process of extracting the base sequence from the Pascal derived sequence as Depascalisation.
Amarnath Murthy, S.E.
core   +1 more source

A Gapless, Unambiguous Genome Sequence of the Enterohemorrhagic Escherichia coli O157:H7 Strain EDL933. [PDF]

open access: yes, 2014
Escherichia coli EDL933 is the prototypic strain for enterohemorrhagic E. coli serotype O157:H7, associated with deadly food-borne outbreaks. Because the publicly available sequence of the EDL933 genome has gaps and >6,000 ambiguous base calls, we ...
Aziz, Ramy K   +4 more
core   +2 more sources

Molecular Epidemiology of O139 Vibrio cholerae: Mutation, Lateral Gene Transfer, and Founder Flush

open access: yesEmerging Infectious Diseases, 2003
Vibrio cholerae in O-group 139 was first isolated in 1992 and by 1993 had been found throughout the Indian subcontinent. This epidemic expansion probably resulted from a single source after a lateral gene transfer (LGT) event that changed the serotype of
Pallavi Garg   +5 more
doaj   +1 more source

BM-BC: A Bayesian Method of Base Calling for Solexa Sequence Data [PDF]

open access: yes, 2012
Base calling is a critical step in the Solexa next-generation sequencing procedure. It compares the position-specific intensity measurements that reflect the signal strength of four possible bases (A, C, G, T) at each genomic position, and outputs ...
Jara, Alejandro   +7 more
core   +2 more sources

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