Unzipping of DNA with correlated base sequence [PDF]
We consider force-induced unzipping transition for a heterogeneous DNA model with a correlated base-sequence. Both finite-range and long-range correlated situations are considered. It is shown that finite-range correlations increase stability of DNA with respect to the external unzipping force. Due to long-range correlations the number of unzipped base-
Allahverdyan, A. +3 more
openaire +7 more sources
Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity
Double-stranded DNA-specific cytidine deaminase (DddA) base editors hold great promise for applications in bio-medical research, medicine, and biotechnology.
Kai Cheng +14 more
doaj +1 more source
Enteropathogenic Escherichia coli O157 Strains from Brazil
We describe two serogroup O157 Escherichia coli strains from Brazilian infants with diarrhea. A variety of assays indicate that these strains belong to the enteropathogenic, not the enterohemorrhagic, pathotype.
T. Eric Blank +5 more
doaj +1 more source
Sequence dependency of canonical base pair opening in the DNA double helix. [PDF]
The flipping-out of a DNA base from the double helical structure is a key step of many cellular processes, such as DNA replication, modification and repair.
Viveca Lindahl +2 more
doaj +1 more source
Sequence-Based Linkage Analysis [PDF]
The rapid decrease in the cost of DNA sequencing will enable its use for novel applications. Here, we investigate the use of DNA sequencing for simultaneous discovery and genotyping of polymorphisms in family linkage studies. In the proposed approach, short contiguous segments of genomic DNA, regularly spaced across the genome, are resequenced in each ...
Furman, Itay +6 more
openaire +2 more sources
Knowledge Modeling in Troubleshooting
Introduction. The article describes the approach to solving the problem of complex technical system troubleshooting based on expert knowledge modeling.
Valeriy P. Dimitrov +2 more
doaj +1 more source
DEPASCALISATION OF SMARANDACHE PASCAL DERIVED SEQUENCES AND BACKWARD EXTENDED FIBONACCI SEQUENCE [PDF]
We call the process of extracting the base sequence from the Pascal derived sequence as Depascalisation.
Amarnath Murthy, S.E.
core +1 more source
A Gapless, Unambiguous Genome Sequence of the Enterohemorrhagic Escherichia coli O157:H7 Strain EDL933. [PDF]
Escherichia coli EDL933 is the prototypic strain for enterohemorrhagic E. coli serotype O157:H7, associated with deadly food-borne outbreaks. Because the publicly available sequence of the EDL933 genome has gaps and >6,000 ambiguous base calls, we ...
Aziz, Ramy K +4 more
core +2 more sources
Molecular Epidemiology of O139 Vibrio cholerae: Mutation, Lateral Gene Transfer, and Founder Flush
Vibrio cholerae in O-group 139 was first isolated in 1992 and by 1993 had been found throughout the Indian subcontinent. This epidemic expansion probably resulted from a single source after a lateral gene transfer (LGT) event that changed the serotype of
Pallavi Garg +5 more
doaj +1 more source
BM-BC: A Bayesian Method of Base Calling for Solexa Sequence Data [PDF]
Base calling is a critical step in the Solexa next-generation sequencing procedure. It compares the position-specific intensity measurements that reflect the signal strength of four possible bases (A, C, G, T) at each genomic position, and outputs ...
Jara, Alejandro +7 more
core +2 more sources

