Results 41 to 50 of about 878,882 (266)

Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations. [PDF]

open access: yesPLoS Computational Biology, 2017
While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood.
Toru Niina   +3 more
doaj   +1 more source

Entering the post-genomic era of malaria research

open access: yesBulletin of the World Health Organization, 2000
The sequencing of the genome of Plasmodium falciparum promises to revolutionize the way in which malaria research will be carried out. Beyond simple gene discovery, the genome sequence will facilitate the comprehensive determination of the parasite?s ...
Horrocks Paul   +4 more
doaj  

Nucleotide Sequence-Based Multitarget Identification [PDF]

open access: yesJournal of Clinical Microbiology, 2003
ABSTRACTMULTIGEN technology (T. Vinayagamoorthy, U.S. patent 6,197,510, March 2001) is a modification of conventional sequencing technology that generates a single electropherogram consisting of short nucleotide sequences from a mixture of known DNA targets. The target sequences may be present on the same or different nucleic acid molecules.
T, Vinayagamoorthy   +2 more
openaire   +2 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Research of Dynamic Wide-gap Frequency Hopping Sequences in Dynamic Spectrum Anti-jamming System [PDF]

open access: yesJisuanji gongcheng, 2018
The existing Frequency Hopping(FH) sequence can not be directly applied to a dynamic spectrum anti-interference system due to poor statistical performance and difficulty in real-time changes of communication parameters.Therefore,a FH sequence suitable ...
LI Shengnan,LI Yonggui,NIU Yingtao,YAN Yan,LUO Jianxiang
doaj  

Complete mitochondrial genome sequence of tufted deer (Elaphodus cephalophus) with phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2019
The complete mitochondrial genome of tufted deer (Elaphodus cephalophus) has been described in our research. The sequence of this genome is 16356 bp with a circular structure, and contains 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two
Lin Zhang   +10 more
doaj   +1 more source

Brain antibody sequence evaluation (BASE): an easy-to-use software for complete data analysis in single cell immunoglobulin cloning

open access: yesBMC Bioinformatics, 2020
Background Repertoire analysis of patient-derived recombinant monoclonal antibodies is an important tool to study the role of B cells in autoimmune diseases of the human brain and beyond.
S. Momsen Reincke   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries. [PDF]

open access: yesPLoS ONE, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
Steven Shave   +4 more
doaj   +1 more source

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