Sequence-dependent base pair stepping dynamics in XPD helicase unwinding
Helicases couple the chemical energy of ATP hydrolysis to directional translocation along nucleic acids and transient duplex separation. Understanding helicase mechanism requires that the basic physicochemical process of base pair separation be ...
Zhi Qi+3 more
doaj +1 more source
A Gapless, Unambiguous Genome Sequence of the Enterohemorrhagic Escherichia coli O157:H7 Strain EDL933. [PDF]
Escherichia coli EDL933 is the prototypic strain for enterohemorrhagic E. coli serotype O157:H7, associated with deadly food-borne outbreaks. Because the publicly available sequence of the EDL933 genome has gaps and >6,000 ambiguous base calls, we ...
Aziz, Ramy K+4 more
core +2 more sources
Base-By-Base Version 3: New Comparative Tools for Large Virus Genomes
Base-By-Base is a comprehensive tool for the creation and editing of multiple sequence alignments that is coded in Java and runs on multiple platforms. It can be used with gene and protein sequences as well as with large viral genomes, which themselves ...
Shin-Lin Tu+5 more
doaj +1 more source
Kraken: ultrafast metagenomic sequence classification using exact alignments
Kraken is an ultrafast and highly accurate program for assigning taxonomic labels to metagenomic DNA sequences. Previous programs designed for this task have been relatively slow and computationally expensive, forcing researchers to use faster abundance ...
Derrick E. Wood, S. Salzberg
semanticscholar +1 more source
SleepEEGNet: Automated sleep stage scoring with sequence to sequence deep learning approach [PDF]
Electroencephalogram (EEG) is a common base signal used to monitor brain activities and diagnose sleep disorders. Manual sleep stage scoring is a time-consuming task for sleep experts and is limited by inter-rater reliability.
Sajad Mousavi, F. Afghah, U. R. Acharya
semanticscholar +1 more source
EvolveAGene 3: A DNA coding sequence evolution simulation program [PDF]
EvolveAGene 3 is a realistic coding sequence simulation program that separates mutation from selection and allows the user to set selection conditions, including variable regions of selection intensity within the sequence and variation in intensity of ...
Barry G. Hall
core +2 more sources
Peak Height Pattern in Dichloro-Rhodamine and Energy Transfer Dye Terminator Sequencing
Establishing the pattern in peak heights within local sequence contexts improves the accuracy of base calling and the identification of DNA sequence variations in dye-terminator cycle sequencing.
H. Zakeri+4 more
doaj +1 more source
This study included 24 isolates of the Candidozyma haemuli species complex from patients in the Brazilian Amazon between 2021 and 2024. These isolates were identified by sequencing as C. duobushaemuli (54.2%), C. haemuli sensu stricto (29.2%), C. haemuli
Sérgio Lobato França+7 more
doaj +1 more source
Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns
Deblur provides a rapid and sensitive means to assess ecological patterns driven by differentiation of closely related taxa. This algorithm provides a solution to the problem of identifying real ecological differences between taxa whose amplicons differ ...
Amnon Amir+10 more
semanticscholar +1 more source
TurboFold: Iterative probabilistic estimation of secondary structures for multiple RNA sequences
Background The prediction of secondary structure, i.e. the set of canonical base pairs between nucleotides, is a first step in developing an understanding of the function of an RNA sequence.
Sharma Gaurav+2 more
doaj +1 more source