Results 51 to 60 of about 2,847,196 (223)
Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity
Molecular Therapy: Nucleic Acids, 2023 Double-stranded DNA-specific cytidine deaminase (DddA) base editors hold great promise for applications in bio-medical research, medicine, and biotechnology.
Kai Cheng +14 more
doaj
The Error and Repair Catastrophes: A Two-Dimensional Phase Diagram in the Quasispecies Model
, 2003 This paper develops a two gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage repair.
A. Giraud +29 more
core +1 more source
Base sequence dependent sliding of proteins on DNA [PDF]
, 2004 The possibility that the sliding motion of proteins on DNA is influenced by the base sequence through a base pair reading interaction, is considered.
A. Travers +7 more
core +3 more sources
Quasi-greedy bases for sequences with gaps
Nonlinear Analysis, 2021 In this paper, we establish new advances in the theory started by T. Oikhberg in [15] where the author joins greedy approximation theory with the use of sequences with gaps. Concretely, we address and partially answer three open questions related to quasi-greedy bases for sequences with gaps posed in [15, Section 6].
M. Berasategui, P.M. Berná
openaire +4 more sources
The nucleotide sequence of a human immnnoglobulin C-gamma-1 gene [PDF]
, 1982 We report the nucleotide sequence of a gene encoding the constant region of a human immnnoglobulin γ1 heavy chain (Cγ1). A comparison of this sequence with those of the Cγ2 and Cγ4 genes reveals that these three human Cγ genes share considerable homology
Berson, Bennett J. +2 more
core
Length-independent DNA packing into nanopore zero-mode waveguides for low-input DNA sequencing [PDF]
, 2017 Compared with conventional methods, single-molecule real-time (SMRT) DNA sequencing exhibits longer read lengths than conventional methods, less GC bias, and the ability to read DNA base modifications.
Henley, Robert Y. +4 more
core +1 more source
Entering the post-genomic era of malaria research
Bulletin of the World Health Organization, 2000 The sequencing of the genome of Plasmodium falciparum promises to revolutionize the way in which malaria research will be carried out. Beyond simple gene discovery, the genome sequence will facilitate the comprehensive determination of the parasite?s ...
Horrocks Paul +4 more
doaj
Mitochondrial DNA. Part B. Resources, 2019 The complete mitochondrial genome of tufted deer (Elaphodus cephalophus) has been described in our research. The sequence of this genome is 16356 bp with a circular structure, and contains 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two
Lin Zhang +10 more
doaj +1 more source
Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations. [PDF]
PLoS Computational Biology, 2017 While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood.
Toru Niina +3 more
doaj +1 more source
BMC Bioinformatics, 2020 Background Repertoire analysis of patient-derived recombinant monoclonal antibodies is an important tool to study the role of B cells in autoimmune diseases of the human brain and beyond.
S. Momsen Reincke +2 more
doaj +1 more source