Results 51 to 60 of about 905,353 (315)

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries. [PDF]

PLoS ONE, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
Steven Shave, Stefan Mann, Joanna Koszela, Alastair Kerr, Manfred Auer   +4 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Improving the specificity of nucleic acid detection with endonuclease-actuated degradation

Communications Biology, 2022
A new method, SENTINEL, improves the specificity of nucleic acid target sequence identification via a combination of isothermal amplification and sequence-specific DNA endonucleases. The method can discriminate single base-pair differences and takes less
Roger S. Zou, Momcilo Gavrilov, Yang Liu, Dominique Rasoloson, Madison Conte, Justin Hardick, Leo Shen, Siqi Chen, Andrew Pekosz, Geraldine Seydoux, Yukari C. Manabe, Taekjip Ha   +11 more
doaj   +1 more source

Gröbner Bases for Increasing Sequences

The Electronic Journal of Combinatorics
Let $q,n \geq 1$ be integers, $[q]=\{1,\ldots, q\}$, and $F$ be a field with $|F|\geq q$. The setof increasing sequences $$I(n,q)=\{(f_1,f_2, \dots, f_n) \in [q]^n:~ f_1\leq f_2\leq\cdots \leq f_n \}$$can be mapped via an injective map $i: [q]\rightarrow F $ into a subset $J(n,q)$ of the affine space $F^n$.
Hegedüs, Gábor, Rónyai, Lajos
openaire   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

بررسی بیوانفورماتیک ارتباط اندازه‌ی ژنوم با خصوصیات ژنتیکی و رفتاری باکتری‌های بیماری‌زا

مجله دانشکده پزشکی اصفهان, 2014
مقدمه: با افزایش تعداد باکتری‌هایی که توالی‌یابی می‌شوند، نیاز به بهره‌برداری از این داده‌ها نیز بیشتر می‌شود. استفاده از این اطلاعات ژنومی از طریق به کارگیری هم‌زمان علوم بیوانفورماتیک و باکتری‌شناسی امکان‌ پذیر می‌باشد.
Mohammad Reza Pourmand, Zahra Pakbaz, Abbas Rahimi-Foroushani, Solmaz Ohadian-Moghadam   +3 more
doaj  

Diagnostic value of 3D-Cube T2 sequence combined with plain CT scan of the skull base for cerebrospinal fluid rhinorrhea

Di-san junyi daxue xuebao, 2019
Objective To evaluate the diagnostic value of magnetic resonance 3D-Cube T2 sequence, plain CT scan of the skull base and their combination for cerebrospinal fluid (CSF) rhinorrhea and assess the performance of these 2 modalities combined in improving ...
GAN Hui, ZHANG Song, JIANG Liling, GE Xiaodong, ZOU Liguang   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Contribution of nonconsensus base pairs within ArsR binding sequences toward ArsR-DNA binding and arsenic-mediated transcriptional induction

Journal of Biological Engineering, 2019
Background A transcriptional reporter is the key component in bacterial biosensors which are employed to monitor the induction or repression of a reporter gene corresponding to environmental change.
Xingjuan Chen, Xin Jiang, Cuijuan Tie, Jinnon Yoo, Yan Wang, Meiying Xu, Guoping Sun, Jun Guo, Xianqiang Li   +8 more
doaj   +1 more source

On-Device Spatial Attention based Sequence Learning Approach for Scene Text Script Identification [PDF]

, 2021
Rutika Moharir, Arun D Prabhu, Sukumar Moharana, Gopi Ramena, Rachit S Munjal   +4 more
openalex   +1 more source