Results 51 to 60 of about 878,882 (266)

Gröbner Bases for Increasing Sequences

The Electronic Journal of Combinatorics
Let $q,n \geq 1$ be integers, $[q]=\{1,\ldots, q\}$, and $F$ be a field with $|F|\geq q$. The setof increasing sequences $$I(n,q)=\{(f_1,f_2, \dots, f_n) \in [q]^n:~ f_1\leq f_2\leq\cdots \leq f_n \}$$can be mapped via an injective map $i: [q]\rightarrow F $ into a subset $J(n,q)$ of the affine space $F^n$.
Hegedüs, Gábor, Rónyai, Lajos
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

بررسی بیوانفورماتیک ارتباط اندازه‌ی ژنوم با خصوصیات ژنتیکی و رفتاری باکتری‌های بیماری‌زا

مجله دانشکده پزشکی اصفهان, 2014
مقدمه: با افزایش تعداد باکتری‌هایی که توالی‌یابی می‌شوند، نیاز به بهره‌برداری از این داده‌ها نیز بیشتر می‌شود. استفاده از این اطلاعات ژنومی از طریق به کارگیری هم‌زمان علوم بیوانفورماتیک و باکتری‌شناسی امکان‌ پذیر می‌باشد.
Mohammad Reza Pourmand, Zahra Pakbaz, Abbas Rahimi-Foroushani, Solmaz Ohadian-Moghadam   +3 more
doaj  

Improving the specificity of nucleic acid detection with endonuclease-actuated degradation

Communications Biology, 2022
A new method, SENTINEL, improves the specificity of nucleic acid target sequence identification via a combination of isothermal amplification and sequence-specific DNA endonucleases. The method can discriminate single base-pair differences and takes less
Roger S. Zou, Momcilo Gavrilov, Yang Liu, Dominique Rasoloson, Madison Conte, Justin Hardick, Leo Shen, Siqi Chen, Andrew Pekosz, Geraldine Seydoux, Yukari C. Manabe, Taekjip Ha   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Diagnostic value of 3D-Cube T2 sequence combined with plain CT scan of the skull base for cerebrospinal fluid rhinorrhea

Di-san junyi daxue xuebao, 2019
Objective To evaluate the diagnostic value of magnetic resonance 3D-Cube T2 sequence, plain CT scan of the skull base and their combination for cerebrospinal fluid (CSF) rhinorrhea and assess the performance of these 2 modalities combined in improving ...
GAN Hui, ZHANG Song, JIANG Liling, GE Xiaodong, ZOU Liguang   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Contribution of nonconsensus base pairs within ArsR binding sequences toward ArsR-DNA binding and arsenic-mediated transcriptional induction

Journal of Biological Engineering, 2019
Background A transcriptional reporter is the key component in bacterial biosensors which are employed to monitor the induction or repression of a reporter gene corresponding to environmental change.
Xingjuan Chen, Xin Jiang, Cuijuan Tie, Jinnon Yoo, Yan Wang, Meiying Xu, Guoping Sun, Jun Guo, Xianqiang Li   +8 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The complete mitogenome and phylogenetic analysis of Japanese firefly ‘Genji Botaru’ Luciola cruciata (Coleoptera: Lampyridae)

Mitochondrial DNA. Part B. Resources, 2017
We performed mitogenome analysis of Japanese firefly Luciola cruciata (Coleoptera: Lampyridae), which is unique species in Japan. It is classified into six haplotypes based on the difference of COII sequence on mitochondrial DNA.
Juri Maeda, Dai-ichiro Kato, Kazunari Arima, Yuji Ito, Atsushi Toyoda, Hideki Noguchi   +5 more
doaj   +1 more source