Results 71 to 80 of about 4,317,506 (277)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Twelve tips for UK medical students undertaking laboratory-based intercalated research projects

MedEdPublish, 2021
Laboratory-based intercalated research projects are a popular undertaking for medical students in the UK. Such projects can provide students with a wealth of valuable experiences and the chance to develop new skills that will be highly beneficial to ...
Lydia Roberts
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Relationship between Academic Motivation and Academic Achievement in Medical Students of Isfahan University of Medical Sciences [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2009
Introduction: Despite their ascribed intellectual ability and achieved academic pursuits, medical students’ academic achievement is influenced by academic motivation.
Samaneh Firouznia, Alireza Yousefi, Gholamreza Ghassemi   +2 more
doaj  

THE METHODOLOGY OF ECONOMICS: AN AGENDA FOR REFORM [PDF]

Uniquely among sciences, the methodology of economics (its epistemology, ontology, scope, and focal questions) has failed to improve the match between its theories and reality.
PETER SMITH
core  

Plenary Panel Discussion: Challenges and opportunities for the future of control [PDF]

, 2005
This panel reflects the scope and diversity of the unprecedented challenges and opportunities for the systems and controls community that has been created by several research themes from the basic sciences to advanced technologies.
Carlson, Jean, Cassandras, Christos, Doyle, John, Kumar, P. R., Leonard, Naomi, Mabuchi, Hideo   +5 more
core  

Menus for Feeding Black Holes

, 2013
Black holes are the ultimate prisons of the Universe, regions of spacetime where the enormous gravity prohibits matter or even light to escape to infinity.
A. Burrows, A. Escala, A. Heger, A. Loeb, A.I. MacFadyen, A.P. Schoenmakers, B. Carter, B. Kocsis, B. Kocsis, B. Kocsis, B. Kocsis, B. Kocsis, B. McKernan, B.A. Fryxell, C. Rodriguez, C. Roedig, C.D. Dermer, C.L. Fryer, D. Merritt, D.N. Burrows, E.C. Ostriker, F. Civano, F. De Colle, F. Hoyle, F. Pretorius, F.D. Lora-Clavijo, F.K. Liu, F.K. Liu, G. Bertone, G. Bertone, G. Fabbiano, G. Lodato, G. Lodato, H. Baumgardt, H. Bondi, H. Bondi, H. Sudou, H.-J. Grimm, I. Mandel, I.D. Novikov, J. Binney, J. Cuadra, J. Frank, J. Goodman, J. Goodman, J. Guilet, J. Guillochon, J. Miralda-Escudé, J. Wang, J.-M. Shi, J.A. Regan, J.G. Baker, J.M. Blondin, J.M. Blondin, J.S.B. Wyithe, J.S.B. Wyithe, J.S.B. Wyithe, K. Belczynski, K. Hayasaki, K. Kotake, K. Nakayama, K.A. Postnov, K.S. Thorne, L. Ballo, L. Blecha, L.E. Strubbe, L.L. Cowie, M. Campanelli, M. Dijkstra, M. Eracleous, M. Freitag, M. Kesden, M. Kesden, M. MacLeod, M. Milosavljević, M. Ruffert, M. Ruffert, M. Saijo, M. Ugliano, M.C. Begelman, M.C. Begelman, M.C. Miller, M.J. Rees, M.J. Rees, M.P. Muno, M.R. Krumholz, M.R. Krumholz, N. Roos, N. Soker, N. Soker, N. Stone, N. Stone, N. Webb, N.I. Shakura, O. Zanotti, P. Goldreich, P. Madau, P. Madau, P. Ranalli, P.B. Ivanov, P.C. Fragile, R. Fernández, R. Haas, R. Narayan, R. Narayan, R. Narayan, R.M. O’Leary, R.M. O’Leary, R.M. O’Leary, R.N. Lang, S. Bianchi, S. Chandrasekhar, S. Gezari, S. Komossa, S. Komossa, S. Mineo, S. Rosswog, S. van Velzen, S.B. Cenko, S.C. Noble, S.F. Portegies Zwart, S.F. Portegies Zwart, S.L. Shapiro, S.L. Shapiro, S.W. Davis, T. Foglizzo, T. Foglizzo, T. Tanaka, U. Anzer, V. Bromm, V. Bromm, V. Paschalidis, X. Chen, Y. Levin, Y. Rephaeli, Y. Shen, Z. Haiman   +136 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Design, Implementation and Evaluation of Electronic Teaching of Practical and Theoretical Histology Courses: a New Experience at Isfahan University of Medical Science [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Electronic education system using advanced and varied technology tries to improve quality of teaching-learning process. This research aimed to design and implement the new electronic teaching system in histology courses (theoretical and ...
Bahman Rashidi, Maryam Avizhgan
doaj  

Basic sciences and nursing [PDF]

Revista Latino-Americana de Enfermagem, 2011
‘Basic sciences’ is a term that refers to studies supporting the range of professional education in different knowledge areas. Basic research, whether in the biological, exact or human area, supports professional practice as well as applied research, even if in the long term.
openaire   +4 more sources