Results 111 to 120 of about 113,312 (290)

IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel [PDF]

, 2011
Background: There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature.
Anibarro B, B. Przybilla, de Larramendi CH, Eberlein-Konig B, F. Ruëff, Freeman GL, Lindemayr H, Majmudar V, Mayoral M, P. Schöpf, Perez, Singh AB, Stadtmauer G, Stockli SS, Stokes JR, T. Herzinger, Vidal C, Williams C   +17 more
core   +1 more source

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source

The JAK1/JAK2 inhibitor ruxolitinib inhibits mediator release from human basophils and mast cells

Frontiers in Immunology
IntroductionThe Janus kinase (JAK) family includes four cytoplasmic tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) constitutively bound to several cytokine receptors. JAKs phosphorylate downstream signal transducers and activators of transcription (STAT).
Remo Poto, Remo Poto, Remo Poto, Leonardo Cristinziano, Leonardo Cristinziano, Leonardo Cristinziano, Gjada Criscuolo, Gjada Criscuolo, Gjada Criscuolo, Caterina Strisciuglio, Francesco Palestra, Francesco Palestra, Gianluca Lagnese, Gianluca Lagnese, Antonio Di Salvatore, Antonio Di Salvatore, Gianni Marone, Gianni Marone, Gianni Marone, Gianni Marone, Giuseppe Spadaro, Giuseppe Spadaro, Giuseppe Spadaro, Stefania Loffredo, Stefania Loffredo, Stefania Loffredo, Stefania Loffredo, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +30 more
doaj   +1 more source

Profiles of Cortisol, Triiodothyronine, Thyroxine and Neutrophil/Lymphocyte Ratio as Stress Indicators in Swamp Buffaloes 15 Days Post-Transportation [PDF]

, 2013
Transportation may cause stress that affects livestock\u27s health. This research was conducted to observe the effect of transportation on the profiles of blood cortisol, triiodothyronine (T3), thyroxine (T4) and neutrophil/lymphocyte (N/L) ratio as ...
Andriani, M. D. (M), andriyanto, A. (andriyanto), Esfandiari, A. (A), Khovifah, A. (A), Maheshwari, H. (H), Yulnawati, Y. (Yulnawati)   +5 more
core  

Clinical efficacy of omalizumab in chronic spontaneous urticaria is associated with a reduction of FcεRI-positive cells in the skin [PDF]

, 2017
Background. Treatment with omalizumab, a humanized recombinant monoclonal anti-IgE antibody, results in clinical efficacy in patients with Chronic Spontaneous Urticaria (CSU). The mechanism of action of omalizumab in CSU has not been elucidated in detail.
Ashton-Chess, Joanna, Bauer, Andrea, Brehler, Randolf, Canvin, Janice, Erpenbeck, Veit J., Georgiou, Panayiotis, Gericke, Janine, Hillenbrand, Rainer, Jarvis, Philip, Kangas, Michael, Maurer, Marcus, Metz, Martin, Staubach, Petra   +12 more
core   +1 more source

Diagnosing Eosinophilic Chronic Rhinosinusitis in Excised Tissue Using Optical Coherence Tomography

The Laryngoscope, EarlyView.
This study evaluated whether optical coherence tomography (OCT) can quantify eosinophils in excised sinonasal tissue and diagnose eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). Counts of globules resembling eosinophils on OCT images strongly correlated with eosinophils per HPF on histology, with a cutoff of 45 globules on OCT imaging ...
Ido Badash, Michael Serafino, Adrian Correa, John S. Oghalai, Bozena Wrobel, Brian E. Applegate, Kevin Hur   +6 more
wiley   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Environmental pollution and climate change seriously affect human health, leading to the onset and exacerbation of chronic respiratory diseases, such as allergic rhinitis and lung diseases. Over the past several decades, increasing air pollution and environmental exposure owing to global urbanization, industrialization, and rapid economic ...
Xin‐Yan Liu, Rui‐Ming Han, Yong‐Tai Wang, Dong‐Dong Zhu, Cui‐Da Meng   +4 more
wiley   +1 more source

Role of Interleukin-33 in Innate-Type Immune Cells in Allergy

Allergology International, 2013
Interleukin-33 (IL-33), a member of the IL-1 cytokine family, is preferentially and constitutively expressed in epithelial cells, and it is especially localized in the cells' nucleus.
Susumu Nakae, Hideaki Morita, Tatsukuni Ohno, Ken Arae, Kenji Matsumoto, Hirohisa Saito   +5 more
doaj   +1 more source