Results 91 to 100 of about 108,915 (302)

Utility of the Basophil Reactivity Test in the Clinical Management of People with Severe Uncontrolled Asthma [PDF]

Maria del Mar García Ródenas,1 Luis Manuel Hernández Blasco,2 Francisco Javier Fernández Sánchez,3 Francisco Manuel Marco de la Calle,4 Jose-Francisco Pascual-Lledó,1 Ángel Sánchez Barbie,5 Cleofé Fernández Aracil2 1Department of Pulmonology, Dr.
García Ródenas MDM, Fernández Sánchez FJ, Fernández Aracil C, Pascual-Lledó JF, Sánchez Barbie Á, Hernández Blasco LM, Marco de la Calle FM   +6 more
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Histamine dilutions modulate basophil activation

, 2004
Background:In order to demonstrate that high dilutions of histamine are able to inhibit basophil activation in a reproducible fashion, several techniques were used in different research ...
Cumps, Jean, Mannaioni, P.F., Roberfroid, Marcel, Wiegant, F.A.C., Mannaioni, P F, Belon, P, Roberfroid, M., Ennis, Madeleine, Wiegant, F A C, Belon, P., Cumps, J., Sainte-Laudy, J., Ennis, M, Sainte-Laudy, J   +13 more
core   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

Food Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid, Muhammad Waqar, Muhammad Tauseef Sultan, Muhammad Maaz, Ahmad Mujtaba Noman, Hassan Raza, Muhammad Israr, Djilali Benabdelmoumene, Abdifetah Ibrahim Omar   +8 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

A Two-Sample Mendelian Randomization Study of Basophil Count and Risk of Gestational Diabetes Mellitus [PDF]

Jing Mao,* Yanqiong Gan,* Xinlin Tan, Yuhan He, Qiao Jing, Qi Shi Affiliated Hospital of North Sichuan Medical College, Nanchong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Shi, Affiliated ...
Tan X, He Y, Shi Q, Jing Q, Gan Y, Mao J
core  

Revealing genetic causality between blood-based biomarkers and major depression in east Asian ancestry

Frontiers in Psychiatry
IntroductionMajor Depression (MD) is a common mental disorder. In East Asian ancestry, the association, causality, and shared genetic basis between blood-based biomarkers and MD remain unclear.MethodsWe investigated the relationships between blood-based ...
Xiaoxiao Mo, Xiaoxiao Mo, Chao Wang, Chao Wang, Qiuyi Pu, Qiuyi Pu, Zhengdong Zhang, Dongmei Wu, Dongmei Wu   +8 more
doaj   +1 more source

Optimizing Laboratory Autoverification in Complete Blood Count Testing Using Machine Learning: A Performance Evaluation Study

Journal of Clinical Laboratory Analysis, EarlyView.
This cross‐sectional study evaluated the feasibility of applying machine learning for complete blood count autoverification. Among 63,201 CBC results, the XGBoost model achieved higher sensitivity and predictive values compared with the traditional rule‐based system. ABSTRACT Background Autoverification improves laboratory efficiency by reducing manual
Sinsorn Srirujee, Peempol Chokchaipermpoonphol   +1 more
wiley   +1 more source

Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice

Frontiers in Immunology, 2018
Ticks are blood-feeding arthropods that can transmit pathogens to humans and animals, leading to serious infectious diseases such as Lyme disease. After single or multiple tick infestation, some animal species develop resistance to tick feeding, leading ...
Yuya Tabakawa, Takuya Ohta, Soichiro Yoshikawa, Elisabeth J. Robinson, Elisabeth J. Robinson, Kayoko Yamaji, Kenji Ishiwata, Yohei Kawano, Kensuke Miyake, Yoshinori Yamanishi, Hiroshi Ohtsu, Takahiro Adachi, Naohiro Watanabe, Hirotaka Kanuka, Hajime Karasuyama   +14 more
doaj   +1 more source

Development of a Machine Learning Algorithm for Differential Diagnosis Between Primary Immune Thrombocytopenia and Connective Tissue Disease‐Related Thrombocytopenia in Pediatric Patients

Journal of Clinical Laboratory Analysis, EarlyView.
Primary immune thrombocytopenia (ITP) and connective tissue disease‐related thrombocytopenia (CTD‐TP) share overlapping initial presentations in children, often leading to delayed diagnosis and suboptimal management. While existing literature focuses on therapeutic strategies, this study is the first to develop a machine learning (ML)‐based diagnostic ...
Furong Kang, Mei Yan, Yingbin Yue, Xuemei Wang, Yu Liu   +4 more
wiley   +1 more source

Basophil activation tests: time for a reconsideration

, 2014
Challenges in in vitro allergy diagnostics lie in the development of accessible and reliable assays allowing identification of all offending allergens and cross-reactive structures.
Uyttebroek, Astrid, Bridts, Chris H, De Clerck, Luc S., Sabato, Vito, Faber, Margaretha A, Lapeere, Hilde, Ebo, Didier, Ebo, Didier G, De Clerck, Luc S, Cop, Nathalie, Faber, Margaretha, Bridts, Christiaan   +11 more
core   +1 more source