Results 111 to 120 of about 108,915 (302)
Basophil-activation tests in hymenoptera allergy
The measurement of basophil-activation markers may be useful in detecting IgIE-mediated sensitization but the relevance for application of the basophil-activation test in prediction of clinical reactivity in Hymenoptera allergy is very limited.
van der Heide, Sicco +1 more
core +1 more source
Role of Interleukin-33 in Innate-Type Immune Cells in Allergy
Interleukin-33 (IL-33), a member of the IL-1 cytokine family, is preferentially and constitutively expressed in epithelial cells, and it is especially localized in the cells' nucleus.
Susumu Nakae +5 more
doaj +1 more source
No Mitoses in Basophilic Erythroblasts
SummaryIn the rabbit, under conditions in which mitoses accumulated in the acidophilic erythroblasts, none were observed in the basophilic erythroblasts. On the basis of certain assumptions, the basophilic erythroblasts were divided into two size classes: of average long diameters (as measured here) 10.3 and 8.4 nm.
H, Borsook, S, Jiggins
openaire +2 more sources
Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin +11 more
wiley +1 more source
Signaling transduction pathways involved in basophil adhesion and histamine release
Little is known about basophil with respect to the different signaling transduction pathways involved in spontaneous, cytokine or anti-IgE induced adhesion and how this compares to IgE-dependent and IgE-independent mediator secretion.
Sha, Quan +4 more
core +1 more source
Background: Immune checkpoint inhibitors (ICI) are increasingly used and are associated with a variety of cutaneous immune-related adverse events (irAEs). While urticarial eruptions are commonly observed in clinical practice, they are rarely described as
Chun-Bing Chen +5 more
doaj +1 more source
Basophil stimulation and signaling pathways
Despite growing use of flow cytometry to analyze the functional characteristics of primary basophils the intracellular signaling cascades that control their ability to elaborate various inflammatory mediators and cytokines remain comparatively obscure ...
Bernhard F. Gibbs +3 more
core +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source

