Results 131 to 140 of about 113,312 (290)
A Straightforward Algorithm for Diagnosing Hymenoptera Venom Allergy and Identifying the Relevant Venom for Immunotherapy
Allergy, EarlyView.Conventional tests, such as specific IgE (sIgE) or intradermal testing (IDT), are usually sufficient. Combining both tests increases sensitivity, while additional tests, like the basophil activation test (BAT), provide no further benefit for the majority of patients.Lisa Arzt‐Gradwohl, Eva Schadelbauer, Urban Čerpes, Gudrun Pregartner, Sereina Annik Herzog, Elisabeth Jungwirth, Karin Laipold, Barbara Binder, Gunter J. Sturm +8 morewiley +1 more sourceNonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study I. clinical findings and in vitro diagnosis [PDF]
, 2009 ackground: We present the results obtained from the largest series of in vitro diagnostic tests ever reported in patients with clinically validated
hypersensitivity to acetylsalicylic acid (ASA)/nonsteroidal anti-infl ammatory drugs (NSAID) compared ...Aberer, W. (W.), Blanca, M. (M.), Correia, S. (S.), Erdman, S. (S.), Gamboa, P.M. (P. M.), Jermann, J.S. (J. S.), Kanny, G. (G.), Kowalski, M. (M.), Mayorga, L. (L.), Medrala, W. (W.), Merk, A. (A.), Sainte-Laudy, J. (J.), Sanz, M.L. (María Luisa), Schneider, M.S. (M.S.), Sczczeklik, A. (A.), Sturm, G.J. (G.J.), Weber, J.M. (J.M.), Weck, A.L. (A.L.) de, Wedi, A. (A.) +18 morecore Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges
Allergy, EarlyView.The threshold of reactivity during fresh milk challenges was 70% lower than that of baked milk challenges, reflecting the higher allergenicity of fresh milk. BAT was the only biomarker statistically significantly different between severity and threshold groups, for baked milk and fresh milk allergies, respectively.Holly Boyd, Irene Bartha, Ru‐Xin Foong, Marta Krawiec, Andreina Marques‐Mejias, Hannah F. Marshall, Suzana Radulovic, Faye Harrison, Grammatiki Antoneria, Zainab Jama, Matthew Kwok, Ewa Pietraszewicz, Malak Eghleilib, Cristian Ricci, Tom Marrs, Gideon Lack, George Du Toit, Alexandra F. Santos +17 morewiley +1 more sourceSequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
Allergy, EarlyView.ABSTRACT
Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.N. A. Nagy, D. Schnoegl, V. Houghton, L. O'Mahony, A. F. Santos, E. F. Knol, A. Kuehn, T. Eiwegger +7 morewiley +1 more sourceHuman KIT Antibody Briquilimab Diminishes Anaphylactic Responses in Mice Expressing Chimeric Human‐Mouse KIT
Allergy, EarlyView.Hye‐Sook Kwon, Song Eun Lee, Ajay Sharma, Minyoung Youn, Charles A. Chang, Andrew Wells, Andrea R. Romo, Allison Ji, Sara Ratia, Sambidhan Kattel, Revati Nerkar, Karl Meneses, Cheryl Kwan, Mang Yu, Wendy W. Pang +14 morewiley +1 more sourceAutoclaved Peanuts Exhibit Reduced Immunoglobulin E Binding and Improved Oral Tolerability
Allergy, EarlyView.This study evaluates the effects of heat and pressure autoclaving on peanut proteins, IgE binding, and oral tolerability.
Heat and pressure autoclaving breaks down peanut proteins and allergens, contributing to reduced peanut‐specific IgE binding.
Autoclaved peanuts are associated with decreased skin test reactivity and greater oral tolerability in ...Casey G. Cohen, Diana Toscano‐Rivero, Eisha A. Ahmed, Adnan Al Ali, Wei Zhao, Danbing Ke, Duncan Lejtenyi, Liane Beaudette, Hana Chazbey, Abdulaziz S. Alrafiaah, Carmen H. Li, Kurt Dejgaard, Albert M. Berghuis, Bertrand J. Jean‐Claude, Christine McCusker, Thomas Eiwegger, Moshe Ben‐Shoshan, Bruce D. Mazer +17 morewiley +1 more sourceSingle‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations
Allergy, EarlyView.Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.Sofia Papavasileiou, Jiezhen Mo, Daryl Boey, Chenyan Wu, Magnus Tronstad, Lucille Margerie, Remi‐André Olsen, Jörg A. Bachmann, Jing Hui Low, Jocelyn Ong, Lars Heede Blom, Anand Kumar Andiappan, Gunnar Nilsson, Joakim S. Dahlin +13 morewiley +1 more sourceThe International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria
Allergy, EarlyView.ABSTRACT
This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...T. Zuberbier, Z. Abdul Hameed Ansari, A. H. Abdul Latiff, M. M. Abuzakouk, M. S. Agcaoili‐De Jesus, R. C. Agondi, M. Al‐Ahmad, A. A. Alangari, H. Alhameli, C. D. Alonso Bello, S. Alshareef, S. Al‐Tamemi, S. Altrichter, H. Al Wahshi, S. Aquilina, M. Araújo, R. Arnaout, R. Asero, B. Ballmer‐Weber, C. Bangert, A. Bauer, M. Ben‐Shoshan, J. A. Bernstein, C. Bindslev‐Jensen, M. Bizjak, I. Boccon‐Gibod, H. Bonnekoh, L. Bouillet, K. Brockow, Z. Brzoza, M. Bulatović Ćalasan, A. Bulkhi, T. Buttgereit, A. Bygum, T. Caballero, O. Calderon, R. Campos, M. Cancian, E. Carne, M. A. Castor, I. Cerecedo, T. Çetinarslan, I. Cherrez‐Ojeda, N. Chkhikvadze, H. J. Chong‐Neto, K. Choo, G. Christoff, C.‐Y. Chu, K. Ciupka, N. Conlon, C. Costa, T. Craig, P. Criado, I. Danilycheva, R. Darlenski, E. De Arruda Chaves, L. de Montjoye, M. S. Doutre, A. Du‐Thanh, D. Ebo, S. Elkhalifa, S. Elmariah, T. El‐Shanawany, L. F. Ensina, R. Ertaş, R. Fachini Jardim Criado, M. Ferrer, S. Ferrucci, J. S. Fok, D. Fomina, L. Fonacier, G. Fouda, I. Francescantonio, A. Fukunaga, C. A. Galvan Calle, E. Garcia, K. Gáspár, A. Gelincik, S. Geng, K. Godse, M. Gonçalo, M. Gotua, C. Grattan, M. Grosber, G. Guidos Fogelbach, M. Guilarte, R. Guillod, E. Hamelmann, J. Hawkes, K. Hayama, R. Heuer, M. Hide, W. Hoetzenecker, N. Inomata, H.‐R. Kang, A. Kaplan, A. Kapp, M. Karam, A. Kasperska‐Zajac, C. H. Katelaris, A. Kessel, M. Khoshkhui, B. Kim, T. Kinaciyan, E. Kocatürk, M. Kolacinska‐Flont, P. Kolkhir, G. N. Konstantinou, M. Kosnik, D. Krasowska, K. Kulthanan, M. S. Kumaran, I. Kuprys‐Lipinska, M. Labrador, J. I. Larco, D. Larenas‐Linnemann, E. Latysheva, E. Lazaridou, P. H. Li, H. Lima, U. Lippert, M. Magerl, M. Makris, J. Alves Marcelino, A. V. Marzano, I. Medina, R. Meshkova, D. Micallef, R. Mohammed Ali, C. G. Mortz, M. Munoz, H. N. G. Oude Elberink, A. Nakonechna, I. Nasr, A. Nast, E. Netchiporouk, E. Nettis, S. Nieto, I. Ogueta Canales, T.‐L. Okas, R. L. Orfali, E. Özkaya, C. Parisi, A. Pennitz, R. Pawankar, M. P. Pereira, J. Peter, E. Petkova, P. D. Pigatto, I. Podder, T. Popov, G. Porebski, P. Pyatilova, G. D. Ramon, H. A. Ratti Sisa, M. Recto, K. Ress, K. Ridge, M. Riedl, C. Ritchie, N. Rosario Filho, I. Rosmaninho, M. Rudenko, M. Rukhadze, K. Rutkowski, V. Sabato, U. M. Sahiner, S. Saini, F. Saleh Al Sabbagh, A. Salman, F. Salvo, J. Sanchez, A. Santucci, S. Schliemann, P. Schmid‐Grendelmeier, B. E. Sekerel, F. Serpa, F. Sheikh, J. Sheikh, H. Shendi, F. Siebenhaar, M. Sonomjamts, A. Soria, B. Sousa Pinto, M. Staevska, P. Staubach, M. Stephan, K. Stevanovic, L. Stingeni, M. Stobiecki, Ö. Su Küçük, G. Sussman, A. Szegedi, S. Takahagi, A. Tanaka, N. Teovska Mitrevska, S. F. Thomsen, E. Toubi, F. Tsatsou, M. Turk, Z. Vadasz, A. Valerieva, S. Valle, M. v. Doorn, B. Veleiro Perez, C. E. Vera Ayala, C. Vestergaard, R. J. Vieira, C. W. Maruta, B. Wedi, R. N. Werner, E. W. Y. Yap, P. Xepapadaki, Y. Xiang, Y.‐M. Ye, P. Yong, G. Yosipovitch, A. Z. J. Zalewska‐Janowska, C. Zeyen, Z. Zhao, M. Metz, A. M. Giménez‐Arnau +221 morewiley +1 more sourceTargeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice
Allergy, EarlyView.ABSTRACT
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui +7 morewiley +1 more source