PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
Basophils drive the resolution and promote wound healing in adult and aged mice. [PDF]
Bex J +23 more
europepmc +1 more source
ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini +6 more
wiley +1 more source
Comparison of allergen types and complete blood count in pediatric allergic rhinitis. [PDF]
Liu L +5 more
europepmc +1 more source
Severe Hair Dye Anaphylaxis Caused by Toluene-2,5- Diamine Identified by Positive in Vitro Tests. [PDF]
Janušonytė E +3 more
europepmc +1 more source
Systemic immunologic effects of long-term dupilumab treatment in severe eosinophilic asthma beyond clinical outcomes. [PDF]
Škrgat S +6 more
europepmc +1 more source
Birch Pollen Exposure Boosts Mal d 1-Specific IgE and Sensitivity to Apple. [PDF]
Litovkina AO +11 more
europepmc +1 more source
Basophil activation to β'-component in adult-onset, salmon roe-induced anaphylaxis. [PDF]
Ugajin T +5 more
europepmc +1 more source
IgE Antibody Function and Mast Cell Activation to Egg in Children Undergoing Baked and Loosely Cooked Egg Challenges. [PDF]
Houghton V +6 more
europepmc +1 more source
Beta Thalassemia and Chronic Myeloid Leukemia: Dual Diagnosis Under the Microscope
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 931-933, October 2026.
Paige Muir +3 more
wiley +1 more source

