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The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease [PDF]
Allergy: European Journal of Allergy and Clinical Immunology, 2015 The basophil activation test (BAT) has become a pervasive test for allergic response through the development of flow cytometry, discovery of activation markers such as CD63 and unique markers identifying basophil granulocytes.
Edward Knol +2 more
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Southern Medical Journal, 1980
We have described a patient with basophilic leukemia secondary to chronic granulocytic leukemia. Symptoms of hyperhistaminemia were aggravated after chemotherapy with hydroxyurea. Antihistamines (H1 receptor antagonists) controlled many of the symptoms related to hyperhistaminemia.
C V, Jennings, C L, Dannaher, L T, Yam
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We have described a patient with basophilic leukemia secondary to chronic granulocytic leukemia. Symptoms of hyperhistaminemia were aggravated after chemotherapy with hydroxyurea. Antihistamines (H1 receptor antagonists) controlled many of the symptoms related to hyperhistaminemia.
C V, Jennings, C L, Dannaher, L T, Yam
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European Journal of Pharmacology, 2016
Basophils are functionally closely related to mast cells. Both cell types express the high-affinity IgE receptor (FcεRI) and rapidly release preformed mediator from intracellular stores upon IgE-mediated activation. However, in contrast to mast cells basophils finish their maturation in the bone marrow and have a lifespan of only 2-3 days.
Christian, Schwartz +2 more
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Basophils are functionally closely related to mast cells. Both cell types express the high-affinity IgE receptor (FcεRI) and rapidly release preformed mediator from intracellular stores upon IgE-mediated activation. However, in contrast to mast cells basophils finish their maturation in the bone marrow and have a lifespan of only 2-3 days.
Christian, Schwartz +2 more
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Specificity of Basophils and Lymphocytes in Cutaneous Basophil Hypersensitivity
The Journal of Immunology, 1975Abstract Using a rosetting technique, it was found that the vast majority of basophils circulating in the blood or accumulating in the skin reactions of guinea pigs primed for cutaneous basophil hypersensitivity (CBH) lacked demonstrable specificity for sensitizing antigen, whether sheep erythrocytes, a soluble protein, or tumor cells ...
H F, Dvorak, R B, Colvin, W H, Churchill
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The expression of CD123 can decrease with basophil activation: implications for the gating strategy of the basophil activation test [PDF]
Clinical and Translational Allergy, 2016 Background: Basophil activation test (BAT) reproduces IgE-mediated allergic reactions in vitro and has been used as a diagnostic test. Different markers can be used to identify basophils in whole blood and have implications for the outcome of the test ...
Gideon Lack +2 more
exaly +2 more sources
Journal of Immunological Methods, 1981
A 3-step procedure is described in detail for producing 50% basophils in 50% yield from human blood. Leukocytes from dextran sedimented blood or preferably whole blood are sedimented on Hypaque-Ficoll, then on aqueous Hypaque, followed by adherence and elution from a column of glass beads.
J J, Pruzansky, R, Patterson
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A 3-step procedure is described in detail for producing 50% basophils in 50% yield from human blood. Leukocytes from dextran sedimented blood or preferably whole blood are sedimented on Hypaque-Ficoll, then on aqueous Hypaque, followed by adherence and elution from a column of glass beads.
J J, Pruzansky, R, Patterson
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Cutaneous basophil hypersensitivity
The American Journal of Dermatopathology, 1984Cutaneous basophil hypersensitivity is a distinct form of hypersensitivity reaction with a delayed-time course that is different from both the classic delayed-type hypersensitivity reaction and immediate hypersensitivity reaction. It occurs in humans, guinea pigs, and other animals. It may be induced by sensitization with a variety of antigens (viruses,
D, Mahapatro, R C, Mahapatro
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Journal of Comparative Pathology, 1987
Leukaemia in an 11-year-old bitch was characterized by the presence in the peripheral blood and bone marrow of cells with lobulated nuclei and numerous metachromatic cytoplasmic granules. The results of cytochemical stains for peroxidase and naphthol AS-D chloracetate esterase activity were negative.
E A, Mahaffey +4 more
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Leukaemia in an 11-year-old bitch was characterized by the presence in the peripheral blood and bone marrow of cells with lobulated nuclei and numerous metachromatic cytoplasmic granules. The results of cytochemical stains for peroxidase and naphthol AS-D chloracetate esterase activity were negative.
E A, Mahaffey +4 more
openaire +2 more sources