Results 181 to 190 of about 72,722 (222)

Basophil Activation Test for Allergy Diagnosis

Journal of Visualized Experiments, 2021
The basophil activation test (BAT) is a complementary in vitro diagnostic test that can be used in addition to clinical history, skin test (ST), and specific IgE (sIgE) determination in the evaluation of IgE-mediated allergic reactions to food, insect venom, drugs, as well as some forms of chronic urticaria.
Inmaculada, Doña, Adriana, Ariza, Tahia D, Fernández, María J, Torres   +3 more
openaire   +2 more sources

Update on the Performance and Application of Basophil Activation Tests [PDF]

Current Allergy and Asthma Reports, 2012
The basophil activation test (BAT) is a flow-cytometry-based functional assay that assesses the degree of cell activation after exposure to a stimuli. Though no standardized technique currently exists, recent advances have improved the performance of this assay, including identification of new basophil-specific markers and comparisons of the expression
Sarbjit Saini
exaly   +3 more sources

Basophil-activation tests in Hymenoptera allergy

Current Opinion in Allergy & Clinical Immunology, 2007
Despite recent advances in our understanding of basophil biology and discovery of new markers for basophil activation, tests measuring basophil activation are not widely utilized in Hymenoptera allergy. Studies of the basophil-activation test in Hymenoptera allergy were examined and the clinical utility of this test was assessed.It has been ...
Anthony E J, Dubois, Sicco, van der Heide   +1 more
openaire   +4 more sources

Methodological cutoff of basophil activation test and basophil activation test diagnostic value

The Journal of Allergy and Clinical Immunology: In Practice, 2018
Methodological cutoff of basophil activation test and basophil activation test diagnostic ...
openaire   +2 more sources

THE BASOPHIL ACTIVATION TEST IN IMMEDIATE DRUG ALLERGY

Acta Clinica Belgica, 2009
Diagnosis of drug allergy is not always straight forward for several reasons. First, a broad spectrum of drugs can elicit various immune-mediated diseases with distinct pathomechanism, secondly, although exact epitope identification is not mandatory for clinical diagnosis, the epitope that causes the reaction is frequently unknown, thirdly in vitro or ...
Ebo, D.G., Hagendorens, M.M., Bridts, C.H., De Clerck, L.S., Stevens, W.J.   +4 more
openaire   +3 more sources

Basophil Activation Test; User's Manual

Journal of Immunological Methods
Immediate allergic responses, orchestrated by basophils and mast cells, are pivotal in severe allergic reactions. The flow cytometry-based Basophil Activation Test (BAT) is a clinically important assay for testing allergic reactions using CD63 and CD203c as endpoints.
Soren Ulrik, Sonder, Matthew, Plassmeyer, Nikhila, Schroeder, Steven, Peyton, Mikell, Paige, Michael, Girgis, Hamed, Safi, Oral, Alpan   +7 more
openaire   +2 more sources

In vitro Tests: Basophil Activation Tests

2007
In recent years, the quantification of basophil activation by flow cytometry (basophil activation test, BAT) has proven to be a useful tool for the assessment of immediate-type responses to ...
María L. Sanz, Pedro M. Gamboa, A.L. De Weck   +2 more
openaire   +1 more source

The Basophil Activation Test in Immediate-Type Drug Allergy

Immunology and Allergy Clinics of North America, 2009
Diagnosis of drug allergy involves first the recognition of sometimes unusual symptoms as drug allergy and, second, the identification of the eliciting drug. This is an often difficult task, as the clinical picture and underlying pathomechanisms are heterogeneous.
Hausmann, Oliver, Gentinetta, Thomas, Bridts, Chris H, Ebo, Didier G   +3 more
openaire   +5 more sources

Basophil Activation Test in Allergy: Time for an Update?

International Archives of Allergy and Immunology, 2012
A wide range of reported evidence in the literature has shown that the quantification of basophil activation by flow cytometry (basophil activation test, BAT) has proven to be a useful tool for the assessment of immediate-type responses to allergens mediated by IgE or other mechanisms in allergic patients.
openaire   +3 more sources

Basophil Activation Tests for Allergy Diagnosis

2009
Peripheral blood basophils and tissue mast cells are primary effector cells in IgEmediated immediate allergic reactions such as rhinitis, asthma, and anaphylaxis. They may also be involved in other kinds of allergic or pseudo-allergic reactions in which other activation mechanisms such as complement activation, non-IgE-mediated stimulation, or non ...
Alain L. de Weck, Maria Luisa Sanz
openaire   +1 more source