Results 1 to 10 of about 34,015 (256)

CD63-snorkel tagging for isolation of exosomes

open access: yesExtracellular Vesicle, 2023
Exosomes (Exo) are important mediators of inter-cellular communications; however, no effective method is available for isolating, thus characterizing, cellular-specific exosomes in vivo.
Chaoshan Han   +10 more
exaly   +5 more sources

Development of a CD63 Aptamer for Efficient Cancer Immunochemistry and Immunoaffinity-Based Exosome Isolation

open access: yesMolecules, 2020
CD63, a member of transmembrane-4-superfamily of tetraspanin proteins and a highly N-glycosylated type III lysosomal membrane protein, is known to regulate malignancy of various types of cancers such as melanoma and breast cancer and serves as a ...
Roberto A Barrero   +2 more
exaly   +3 more sources

Epstein-Barr Virus LMP1 Modulates the CD63 Interactome [PDF]

open access: yesViruses, 2021
Tetraspanin CD63 is a cluster of cell surface proteins with four transmembrane domains; it is associated with tetraspanin-enriched microdomains and typically localizes to late endosomes and lysosomes.
Mujeeb Cheerathodi   +4 more
doaj   +3 more sources

A nanobody against CD63 for non-destructive exosome labeling [PDF]

open access: yesBiology Direct
Exosomes, also known as small extracellular vesicles, play crucial roles in cancer progression, inflammation, and tissue regeneration, serving as emerging platforms for diagnostics and therapeutic delivery. However, specific and high-affinity binders for
Siyu Chen   +6 more
doaj   +2 more sources

In‐Solution Characterization of Extracellular Vesicles: A New Approach to Evaluating Antibody Binding and Surface Interactions [PDF]

open access: yesJournal of Extracellular Vesicles
Extracellular vesicles (EVs) are emerging as diagnostic and therapeutic agents, yet their nanoscale size limits quantitative single‐vesicle analysis of surface epitopes and molecular interactions. Flow‐Induced Dispersion Analysis (FIDA) is a microfluidic
Maria‐Anthi Kakavoulia   +10 more
doaj   +2 more sources

Immuno-phenotyping of IDH-mutant grade 3 astrocytoma and IDH-wildtype glioblastoma reveals specific differences in cells of myeloid origin

open access: yesOncoImmunology, 2021
Gliomas are heavily infiltrated with immune cells of myeloid origin. Past studies have shown that high-grade gliomas have a higher proportion of alternatively activated and suppressive myeloid cells when compared to low-grade gliomas, which correlate ...
Jayashree V. Raghavan   +14 more
doaj   +1 more source

Assembly of tetraspanins, galectin-3, and distinct N-glycans defines the solubilization signature of seminal prostasomes from normozoospermic and oligozoospermic men

open access: yesUpsala Journal of Medical Sciences, 2021
Background: Prostasomes, extracellular vesicles (EVs) abundantly present in seminal plasma, express distinct tetraspanins (TS) and galectin-3 (gal-3), which are supposed to shape their surface by an assembly of different molecular complexes.
Tamara Janković   +5 more
doaj   +1 more source

Tetraspanin CD63 reduces the progression and metastasis of head and neck squamous cell carcinoma via KRT1-mediated cell cycle arrest

open access: yesHeliyon, 2023
Despite the fact that metastasis is the leading cause of death in patients with head and neck squamous cell carcinoma, fundamental questions about the mechanisms that enable or inhibit metastasis remain unanswered.
Qiang Huang   +11 more
doaj   +1 more source

Clinico-pathological significance of exosome marker CD63 expression on cancer cells and stromal cells in gastric cancer. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:It has been reported that CD63, an exosome marker, is expressed in solid cancer tissues. However, its significance in patients with gastric cancer has not been clarified.
Yuichiro Miki   +6 more
doaj   +1 more source

CD63 and C3AR1: The Potential Molecular Targets in the Progression of Septic Shock

open access: yesInternational Journal of General Medicine, 2022
Ning Yu, Xuefang Liu, Dandan Shi, Long Bai, Tianfu Niu, Ya Liu Department of Anaesthesiology and Intensive Care, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050004, People’s Republic of ChinaCorrespondence: Ya Liu,
Yu N, Liu X, Shi D, Bai L, Niu T, Liu Y
doaj  

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