Results 41 to 50 of about 34,015 (256)
Advanced Functional Materials, EarlyView.This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu +14 more
wiley +1 more source
A cell-based assay for CD63-containing extracellular vesicles [PDF]
PLOS ONE, 2019 Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of disease. However, quantitative methods to enable elucidation of mechanisms underlying release are few.
Anil G. Cashikar, Phyllis I. Hanson
openaire +4 more sources
CD63 orchestrates ferritin export [PDF]
Blood, 2021 Suzy V, Torti, Frank M, Torti
openaire +2 more sources
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria [PDF]
Annals of Dermatology, 2013 Hans Jurgen Hoffmann, Allergy Center for West Denmark, Department of Pulmonary Medicine, Health: Aarhus Uni-versity, Building 2b, Norrebrogade 44, DK 8000 Aarhus C, Denmark. Tel: 45-78462107, Fax: 45-78462110, E-mail: hans.jurgen.hoffmann @ki.au.dkThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non ...
Christensen, Claus Uhrenholt +2 more
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CD63 Promotes Hemocyte-Mediated Phagocytosis in the Clam, Paphia undulata
Journal of Immunology Research, 2016 As one of the surface membrane proteins of tetraspanin family, CD63 plays a crucial role in cellular trafficking and endocytosis, which also is associated with activation of a wide variety of immune cells. Here, the homolog of CD63 was characterized from
Mingjia Yu +3 more
doaj +1 more source
Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
RNF149 negatively regulates LPS/TLR4 signal transduction by ubiquitination-mediated CD63 degradation
HeliyonThis study aims to investigate the role of RNF149 and tetraspanin CD63 in lipopolysaccharide/Toll-like receptor 4 (LPS/TLR4) signal transduction. TNF-α was assessed using enzyme-linked immunosorbent assay.
Xiu-An Yang +6 more
doaj +1 more source
BMC Immunology, 2021 Background No reliable biological marker for the diagnosis of asthma in younger children is currently available. In this study, we analyzed the differences in basophil activation test (BAT) results among children with recurrent wheezing episodes who had ...
Jingyang Li +9 more
doaj +1 more source
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source