Results 11 to 20 of about 34,015 (256)
Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles [PDF]
Frontiers in Microbiology, 2017 CD63, a member of the tetraspanin family, is involved in virion production by human immunodeficiency virus type 1 (HIV-1), but its mechanism is unknown. In this study, we showed that a small GTP-binding protein, Rab3a, interacts with CD63. When Rab3a was
Yoshinao Kubo +8 more
doaj +3 more sources
Exosomal CD63 in critically ill patients with sepsis [PDF]
Scientific Reports, 2021 CD63 is one of the tetraspanin protein family members that is ubiquitously expressed on exosomes and is involved in the signal transduction of various types of immune cells.
Yunjoo Im +5 more
doaj +3 more sources
The Immunohistochemically Estimation of CD63 in Iraqi Patients with Gastric Cancer
مجلة بغداد للعلوم, 2022 CD63 is -one of the tetraspanin family proteins, which are regarded as: hallmark exosomal markers because it is absent from other types of vesicles. It is expressed in the cell membrane of cancer cells, and cytoplasm of stromal cells.
Raghad Khalid Mwafaq +3 more
doaj +2 more sources
Protein kinase activity is associated with CD63 in melanoma cells [PDF]
Journal of Translational Medicine, 2005 Background The tetraspan protein CD63, originally described as a stage-specific melanoma antigen but also present in a number of normal cells, regulates melanoma cell growth in nude mice, motility in serum containing media, and adhesion to several ...
McCarthy James B +3 more
doaj +3 more sources
Regulation of zebrafish hatching by tetraspanin cd63.
PLoS ONE, 2011 Tetraspanins cause the clustering of membrane proteins into a level of organisation essential for cellular function. Given the importance and complicated nature of this mechanism, we attempted a novel approach to identify the function of a single ...
Michael Z Trikić +3 more
doaj +5 more sources
BAP31 Drives Cartilage Calcification through Disruption of Autophagosome-Lysosome Fusion in Osteoarthritis. [PDF]
Adv Sci (Weinh)Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Xu ZH +13 more
europepmc +2 more sources
Platelets, 2017 Cells release membrane vesicles in their surrounding medium either constitutively or in response to activating signals. Two main types of extracellular vesicles (EVs) are commonly distinguished based on their mechanism of formation, membrane composition ...
Alain R. Brisson +4 more
doaj +1 more source
Journal of Extracellular Vesicles, 2019 Extracellular vesicles (EVs) mediate targeted cellular interactions in normal and pathophysiological conditions and are increasingly recognised as potential biomarkers, therapeutic agents and drug delivery vehicles.
André Görgens +17 more
doaj +1 more source
Immunofluorescence of ATP13A2 and CD63 v1
, 2023 This protocol describes the seeding, fixation and staining of samples for immunofluorescent visualization of ATP13A2 and CD63.
Stephanie Vrijsen, Peter Vangheluwe
openaire +1 more source
Molecular Mechanisms Underlying the Cellular Entry and Host Range Restriction of Lujo Virus
mBio, 2022 Like other human-pathogenic arenaviruses, Lujo virus (LUJV) is a causative agent of viral hemorrhagic fever in humans. LUJV infects humans with high mortality rates, but the susceptibilities of other animal species and the molecular determinants of its ...
Takeshi Saito +6 more
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