Results 71 to 80 of about 72,722 (222)

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

open access: yesPhytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin   +7 more
wiley   +1 more source

Commentary: The Expression of CD123 Can Decrease with Basophil Activation: Implications for the Gating Strategy of the Basophil Activation Test [PDF]

open access: yesFrontiers in Immunology, 2016
Basophil activation test (BAT) is an assay used to diagnose allergy by evaluating the expression of surface molecules in circulating and activated basophils with an in vitro flow cytometry (FC) approach. Separation of basophils from whole blood is virtually made by an electronic capture in FC.
openaire   +2 more sources

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

open access: yesSmall, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros   +2 more
wiley   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin   +11 more
wiley   +1 more source

A Case of Anaphylactic Reaction Following Matsutake Mushroom Ingestion: Demonstration of Histamine Release Reaction of Basophils

open access: yesAllergology International, 2010
Background: Matsutake mushroom is not recognized as a common food allergen. However, several case reports have suggested that this mushroom can induce anaphylaxis on rare occasions.
Takako Toda   +6 more
doaj   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

open access: yesAllergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller   +16 more
wiley   +1 more source

The utility of the basophil activation test in the diagnosis of immediate amoxicillin or amoxicillin-clavulanate hypersensitivity in children and adults

open access: yesItalian Journal of Pediatrics, 2017
Background The basophil activation test (BAT), has been proposed as a possible assay for the diagnosis of immediate-type allergy to beta-lactams (BLs).
Simona Barni   +10 more
doaj   +1 more source

Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis

open access: yesAllergy, EarlyView.
Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb
Rosa Alba Sola‐Martinez   +9 more
wiley   +1 more source

BASOPHIL ACTIVATION TEST (BAT) IN »IN VITRO« DIAGNOSIS OFHYMENOPTERA VENOM HYPERSENSITIVITY

open access: yesZdravniški Vestnik, 2008
BACKGROUND The basophil activation test relies on flow cytometric quantitation of the expression of themarkers on the surface of basophils, after stimulation with the amount of allergen thatcross-link IgE antibodies bound on their surface.
Andreja Peternelj   +5 more
doaj  

INTENSITY OF SPECIFIC SENSITIZATION AND IMMUNE PROFILE IN PATIENTS WITH BRUCELLOSIS

open access: yesМедицинская иммунология, 2016
The authors propose a new methodological approach to rapid intensity assessment of specific sensitization in acute brucellosis. This technique shows high sensitivity (98%), and specificity (97%).
N. S. Sarkisуan   +5 more
doaj   +1 more source

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