Results 181 to 190 of about 56,684 (297)

Blood Cell Counts and the Duffy Null Phenotype: Beyond Neutropenia

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT The absence of Duffy antigen expression on red blood cells, caused by a single nucleotide polymorphism in the DARC/ACKR1 gene, confers protection against malaria and is associated with lower absolute neutrophil counts (ANC) in some studied populations.
Elvira Deolinda R. P. Velloso, Andreza Oliveira dos Santos, Carla Luana Dinardo, Carolina Bonet Bub, Leandro Dinalli Santos, Mauren Fernanda Moller dos Santos, João Carlos de Campos Guerra, Denise dos Anjos Laurentis de Sousa Campos, Monica Juliana Vieira, Fábio Julio da Luz, Alfredo Mendrone‐Junior, Rosana M. Cosentino Penteado   +11 more
wiley   +1 more source

Basophils drive the resolution and promote wound healing in adult and aged mice. [PDF]

J Exp Med
Bex J, Peter V, Saji C, Dupont C, Lavernhe M, Jin S, Chapart L, Gautier G, Thibaudeau O, Thaminy MK, Tchen J, Simon Q, Dai X, Miyake K, Karasuyama H, Jiang JX, Naidoo K, Benhamou M, Blank U, Monteiro RC, Le Gros G, Coste A, Charles N, Pellefigues C.   +23 more
europepmc   +1 more source

Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection

Immunology &Cell Biology, EarlyView.
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg, Carly Kadonoff, Bailey Lehnert, Priyanka Pundir   +3 more
wiley   +1 more source

The alpha-gal syndrome: Understanding the role of tick bites, and the delays in severe anaphylaxis. [PDF]

Allergy Asthma Proc
Platts-Mills TAE, Dunaway CA, Gangwar RS, Workman LJ, Wilson JM.   +4 more
europepmc   +1 more source

Evaluation of Methods for Identifying Human Monocytes by Flow Cytometry: TLR2 May be an Optimal Marker

Immunology, EarlyView.
Monocytes play crucial roles in the pathobiology of a wide range of medical conditions, including infection, autoimmunity, cardiovascular disease and malignancies. Studies using flow cytometry revealed the complexity of monocyte biology, including the identification of three human monocyte subsets: classical (CD14pos CD16neg), intermediate (CD14pos ...
Mie Wolff Kristensen, Katrine Skjøt Harbo, Thomas Vorup‐Jensen, Marianne Hokland, Morten Nørgaard Andersen   +4 more
wiley   +1 more source

Dysregulated expression of PSGL-1 and ADAM8 in Sjögren's disease: potential contribution to disease pathogenesis. [PDF]

Front Immunol
Ramos-Manzano A, Sánchez-Abad I, San Antonio E, Uriarte-Ecenarro M, González-Álvaro I, Saez-Martínez JC, Dueñas-Ochoa M, García-Pérez J, Ancochea J, Vicente-Rabaneda EF, Castañeda S, Urzainqui A.   +11 more
europepmc   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Single-cell transcriptomics of granulocytes in asthma and atopic diseases. [PDF]

Front Mol Biosci
Hogan NT, Garduno A, Santos F, Winata E, Pabalate JW, Akuthota P, Seumois G.   +6 more
europepmc   +1 more source

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

Basophil [PDF]

, 2008
openaire   +2 more sources