Results 181 to 190 of about 53,289 (299)

CH50 as a Clinically Useful Biomarker of Disease Activity and Antihistamine Resistance in Chronic Spontaneous Urticaria: An Observational Ambispective Single‐Center Study

International Journal of Dermatology, EarlyView.
Personalized CSU care guided by CH50. ABSTRACT Background Chronic spontaneous urticaria (CSU) is frequently refractory to guideline‐based therapy, highlighting the need for predictive biomarkers. Dysregulation of the complement system has been implicated in CSU severity, but global complement activity has not been systematically evaluated.
Nidia Planella‐Fontanillas, Emilio Berna‐Rico, David Pesqué, Evelyn Andrades, Silvia Sánchez, Paloma Torres‐Bosó, Ramon Gimeno, Fernando Gallardo, Ramon M. Pujol, Ana M. Giménez‐Arnau   +9 more
wiley   +1 more source

IL-33 and IL-3 synergistically induce CD25 expression on human basophils without functional IL-2 signaling: a potential marker of severe COVID-19. [PDF]

Front Immunol
Retnakumar SV, Singh SC, Chauvin C, Bayry J.   +3 more
europepmc   +1 more source

Evaluating Basophil Histamine Content as a Biomarker for Omalizumab Responsiveness in Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, EarlyView.
Ditte Georgina Zhang, Katrine Baumann, Clive Grattan, Per Stahl Skov, Simon Francis Thomsen   +4 more
wiley   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

International Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad, Nicole E. Chin, Raj Chovatiya   +2 more
wiley   +1 more source

Analytical and Clinical Performance of the Atellica HEMA 580 Haematology Analyzer: A Comparison With the ADVIA 2120i

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The Atellica HEMA 580 is a novel haematology analyser providing eight‐part leukocyte differential and optical platelet (PLT) counting. We compared its analytical and clinical performance with that of the ADVIA 2120i. Methods A total of 796 residual whole blood specimens were analysed.
Hyeongyu Lee, Jooyoung Cho, Gilsung Yoo, Juwon Kim   +3 more
wiley   +1 more source

Mast cell specific Cyp11a1 deficiency promotes T cell mediated immunity and suppresses tumour metastasis in a mouse model of melanoma. [PDF]

Sci Rep
Alim MA, Butcher K.
europepmc   +1 more source

Assessment of the Performance of Siemens Scopio Digital Morphology on Bone Marrow Aspirates in Onco‐Hematology

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini, John Marra, Elena Rossi, Silvia Bellesi, Nicoletta Pelliccioni, Giuseppe d'Onofrio, Patrizia Chiusolo   +6 more
wiley   +1 more source

Basophils in atopic dermatitis: Immunologic roles and clinical implications. [PDF]

Ann Allergy Asthma Immunol
Das M, Geha RS.
europepmc   +1 more source

A Meta‐Analysis of Anti‐Thyroid Peroxidase Antibody and Omalizumab Response in Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, EarlyView.
Ju Hyun Lee, Min Jung Geum, Do‐Young Kim, Young‐Mi Ah, Yun Mi Yu   +4 more
wiley   +1 more source

Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production. [PDF]

Front Immunol
Peng J, Sy CB, Zhao S, Sawhney A, Espinosa V, Schroeter MN, Ponessa JJ, Chavan K, Lemenze AD, Rivera A, Rohacs T, Siracusa MC.   +11 more
europepmc   +1 more source