Basophil FCER1A and PTAFR Gene Expression Profiles Correlate With Disease Severity in Chronic Spontaneous Urticaria. [PDF]
Soetanto KM +5 more
europepmc +1 more source
Understanding Prebiotic Allergy: An Evaluation of Basophil Activation Induced by Galacto-Oligosaccharides. [PDF]
Leow SY +10 more
europepmc +1 more source
Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward
ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim +10 more
wiley +1 more source
Chronic myeloid leukemia presenting with isolated central nervous system lymphoid blast crisis: A case report. [PDF]
Zarama-Valenzuela Á +3 more
europepmc +1 more source
Chinese Position Paper on Biologic Therapy for Allergic Rhinitis
ABSTRACT Allergic rhinitis (AR) is a common, persistent nasal disorder that poses significant public health challenges worldwide. Current treatment options frequently fail to achieve adequate symptom control in a substantial subset of patients. Over the past two decades, biologic therapies that target type 2 inflammatory pathways have been used to ...
Yuan Zhang +37 more
wiley +1 more source
IgE Nonresponders in Basophil Activation Tests: A Narrative Review From Mechanistic Insights to Clinical Implications and Future Directions. [PDF]
Eberlein B, Biedermann T.
europepmc +1 more source
IL-33 and IL-3 synergistically induce CD25 expression on human basophils without functional IL-2 signaling: a potential marker of severe COVID-19. [PDF]
Retnakumar SV +3 more
europepmc +1 more source
Hypersensitivity to Excipients in Drugs: An EAACI Position Paper
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey +10 more
wiley +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Basophil activation to β'-component in adult-onset, salmon roe-induced anaphylaxis. [PDF]
Ugajin T +5 more
europepmc +1 more source

