Results 151 to 160 of about 56,684 (297)

Diagnostic Performance of Recombinant Peanut Allergens in Children: sIgE Cut‐Offs and Anaphylaxis Risk

Acta Paediatrica, EarlyView.
Diagnostic performance of recombinant peanut allergens for anaphylaxis risk in children. (A) Study population and clinical group. (B) Component‐specific IgE cut‐offs and associated odds ratios. (C) Forest plot of odds ratios for anaphylaxis. (D) Clinical interpretation of component‐specific IgE cut‐offs. ABSTRACT Aim Component‐resolved diagnostics (CRD)
Lisa Gazzolari, Annamaria Porreca, Marianna D'Andrea, Claudia Sala, Maurizio Pizzoli, Franca Faraoni, Paola Di Filippo, Dorina Hoxha, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi   +10 more
wiley   +1 more source

Factors Associated With Omalizumab Response in Chronic Spontaneous Urticaria: Are There Age‐Related Differences?

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study aimed to explore clinical and laboratory markers of omalizumab response in paediatric and adult chronic spontaneous urticaria (CSU) patients. Methods The study included 32 children and 67 adults with CSU receiving omalizumab, and 29 paediatric and 30 adult healthy controls; associations with treatment response were evaluated ...
Güler Yıldırım Nalbant, Raif Coşkun, Nilay Çalışkan, Merve Karaca Şahin, Aslı Berivan Topçak, Muhammed Fatih Erbay, Çağla Öztürk Turan, Hilal Güngör, Hamit Boloğur, Hasan Tunç Şarman, Şule Papağan, Ömer Yılmaz Ulutaş, Şefika İlknur Kökçü Karadağ, Özlem Terzi, Deniz Özçeker   +14 more
wiley   +1 more source

Basophil-specific deletion of interleukin 15 impairs memory CD8⁺ T cell homeostasis in the bone marrow. [PDF]

Front Immunol
Stecher C, Neuwirth I, Begunic A, Braun N, Herndler-Brandstetter D.   +4 more
europepmc   +1 more source

Allergenicity of α‐Gal‐Containing Products

Allergy, EarlyView.
Frederik Bloch Mangaard, Esben Eller, Per Stahl Skov, Charlotte G. Mørtz, Carsten Bindslev‐Jensen   +4 more
wiley   +1 more source

A Real‐World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Among patients with severe eosinophilic asthma, benralizumab was associated with greater improvements in asthma outcomes—such as improved asthma control, quality of life and remission rates—compared to biologic‐naïve patients. ABSTRACT Background Real‐world data on benralizumab in patients with severe eosinophilic asthma–while controlling for ...
Dennis Thomas, Vanessa M. McDonald, Gijo Thomas, Joy Lee, Li Ping Chung, Matthew Peters, Shakti D. Shukla, Yuto Hamada, Erin S. Harvey, Michael Fricker, Hayley See, Rejoy Sabin Thomas, Claude S. Farah, Andrew Gillman, Constance H. Katelaris, Gregory P. Katsoulotos, David Langton, Peter G. Middleton, Paul Reynolds, Janet Rimmer, Francis Thien, Stephen Vincent, John W. Upham, Peter G. Gibson   +23 more
wiley   +1 more source

Berberine Inhibits Eczematous Skin <i>S. aureus</i>-Induced Mast Cell/Basophil Activation and Modulates MAPK-Associated Gene Expression. [PDF]

Int J Mol Sci
Maskey AR, Kopulos D, Spears M, Wang ZZ, Mo X, Musa I, Yang N, Nowak-Wegrzyn A, Chung D, Maitland AL, Wang J, Tiwari RK, Sampson HA, Geliebter J, Li XM.   +14 more
europepmc   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Associations between prenatal phthalate exposure and maternal immune cell profiles across trimesters. [PDF]

Front Public Health
Zhang Y, Tao L.
europepmc   +1 more source

IgE levels correlate with Fc<i>ε</i>RI expression on circulatory basophils but not with their activation response in patients with Hymenoptera anaphylaxis. [PDF]

Front Allergy
Aigner S, Puxkandl V, Burner T, Lackner A, Moñino-Romero S, Giménez-Arnau AM, Kimeswenger S, Gabriel M, Hoetzenecker W, Altrichter S.   +9 more
europepmc   +1 more source

The PGD₂/DP2 axis promotes pro-inflammatory responses but attenuates an antigen-presenting role of human basophils. [PDF]

Commun Biol
Luo J, Chen W, Lett MJ, Yu S, Luo W, Coakley E, Kazani S, Shikatani EA, Hinks TSC, Sandham DA, Pavord ID, Klenerman P, Xue L.   +12 more
europepmc   +1 more source