Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
Cell, 1995 Miyashita Toshiyuki, John Calvin Reed
semanticscholar +1 more source
Altered bcl-2 and bax Expression and Intracellular Ca2+ Signaling in Apoptosis of Pancreatic Cells and the Impairment of Glucose-Induced Insulin Secretion* [PDF]
, 1998 N. Mizuno +6 more
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Advanced Science, EarlyView.A novel Janus Ag/Ag2S nanostructure grafted with dimer PD‐L1 affibody (AMZ) is successfully developed. AMZ can be used as ROS nanocatalyst to achieve tumor radiosensitization, and it can also act as an ROS eliminator to alleviate radiation enteritis, achieving a radiotherapy strategy characterized by “toxicity reduction and efficacy enhancement ...
Mengmeng Zhang +12 more
wiley +1 more source
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy
Nature Cancer, 2020 Dulguun Amgalan +31 more
semanticscholar +1 more source
Advanced Science, Volume 12, Issue 28, July 24, 2025.The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song +13 more
wiley +1 more source
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
Science, 2018 K. McArthur +24 more
semanticscholar +1 more source
Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment [PDF]
, 1998 Tohru Kobayashi +9 more
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Advanced Science, EarlyView.The role of splicing factor 3A subunit 3 (SF3A3) in driving endometrial cancer (EC) progression and potential therapeutic interventions. SF3A3, a core component of the U2 small nuclear ribonucleoprotein (U2 snRNP), is upregulated in endometrial cancer (EC) and promotes tumor growth and cisplatin resistance. RNA‐binding protein immunoprecipitation (RIP)
Wei Yu +13 more
wiley +1 more source
Bax, Bak and beyond — mitochondrial performance in apoptosis
The FEBS Journal, 2018 Aida Peña-Blanco, A. García-Sáez
semanticscholar +1 more source
Bax-α promotes apoptosis induced by cancer chemotherapy and accelerates the activation of caspase 3-like cysteine proteases in p53 double mutant B lymphoma Namalwa cells [PDF]
, 1998 Estelle Schmitt +3 more
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