Results 171 to 180 of about 150,507 (294)

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

open access: yesPhytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao   +13 more
wiley   +1 more source

GENE (p53, c-myc, bcl-2, fas, bax, mdr-1) REGULATION OF CHEMOTHERAPY - INDUCED APOPTOSIS DURING THE TREATMENT OF ACUTE LEUKEMIAS [PDF]

open access: bronze, 1999
George Th. Tsangaris   +3 more
openalex   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

open access: yesRare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang   +9 more
wiley   +1 more source

A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast [PDF]

open access: bronze, 2001
Evgeny V. Pavlov   +8 more
openalex   +1 more source

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