Results 171 to 180 of about 221,308 (340)

Robotic Interventional Needle Insertion Assisted by a Cable‐Driven Parallel Robot

open access: yesAdvanced Intelligent Systems, EarlyView.
This article presents a body‐mounted cable‐driven parallel robot assisting the needle insertion procedure designated for automated interventional pain therapy. The 3D‐printed robot body and multiple thin cables can achieve high X‐ray compatibility for intervention. The robot performs full 6‐degree of freedom needle insertion and remote center of motion
Myungjin Jung   +5 more
wiley   +1 more source

Phosphorylation of Bcl-2 and Bax Proteins During Acute Hypoxia in Cerebral Cortical Nuclei of the Guinea Pig Fetus • 1889 [PDF]

open access: bronze, 1998
Om P. Mishra   +3 more
openalex   +1 more source

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T‐Cell Lymphoma

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Nodal follicular helper T‐cell (TFH) lymphoma of the angioimmunoblastic (AITL) subtype has a dismal prognosis. Using whole‐exome sequencing (n = 124), transcriptomic (n = 78), and methylation (n = 40) analysis, we identified recurrent mutations in known epigenetic drivers (TET2, DNMT3A, IDH2R172) and novel ones (TET3, KMT2D).
Alyssa Bouska   +43 more
wiley   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai   +8 more
wiley   +1 more source

Effects of concurrent regular aerobic training and garlic extract on cardiac tissue apoptosis markers in aged rats with chronic kidney disease

open access: yesJournal of Medicinal Plants, 2017
Background: One of the problems due to aging is apoptosis development in various tissues of body. There is some evidence that some drugs induce apoptosis development via oxidative stress.
Zeynab Razavi Majd   +3 more
doaj  

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.

open access: yesMolecules and Cells, 2001
E. Cheng   +6 more
semanticscholar   +1 more source

The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21 BAX expression

open access: green, 1998
Hui‐Kuo G. Shu   +5 more
openalex   +1 more source

Immunohistochemical Study for Expression of p53, bcl-2 and Bax in Uterine Sarcoma [PDF]

open access: bronze, 1997
Hyung Sik Chu   +9 more
openalex   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang   +6 more
wiley   +1 more source

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