Results 71 to 80 of about 298,121 (314)
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway [PDF]
Molecular Cell, 2016 Pro-apoptotic BAX is a cell fate regulator playing an important role in cellular homeostasis and pathological cell death. BAX is predominantly localized in the cytosol, where it has a quiescent monomer conformation. Following a pro-apoptotic trigger, cytosolic BAX is activated and translocates to the mitochondria to initiate mitochondrial dysfunction ...
Hui Chen Chen +9 more
openaire +6 more sources
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEBS Open Bio, EarlyView.FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang +5 more
wiley +1 more source
Sharp Frequency Bounds for Sample-Based Queries [PDF]
In 2019 IEEE Big Data, pages 5983-5985, 2019, 2022 A data sketch algorithm scans a big data set, collecting a small amount of data -- the sketch, which can be used to statistically infer properties of the big data set. Some data sketch algorithms take a fixed-size random sample of a big data set, and use that sample to infer frequencies of items that meet various criteria in the big data set.
arxiv
Advanced Biology, EarlyView.The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua +5 more
wiley +1 more source
Effect of aerobic exercise on some factors of cardiac apoptosis in male rats
Fiyz̤, 2019 Background: Cardiac apoptosisplays an important role in myocardial diseases. Current evidence suggests that exercise training may modify some apoptosis-related signaling in myocardium.
Sadighi A +3 more
doaj
Evaluating the effects of hypoxia and taper on expression of Pulmonary Bax and Bcl2 apoptotic proteins [PDF]
Journal of Advanced Biomedical Sciences, 2018 Background & Objective: Due to The limitation of research literature, related to the effect of exercise training with different intensity, Along with Hypoxia Stress on Pulmonary Apoptosis, The purpose of this study was to investigate the effects of ...
Mehdi Yadegari +5 more
doaj
Do diverse and inclusive workplaces benefit investors? An Empirical Analysis on Europe and the United States [PDF]
arXiv, 2022 As the COVID-19 pandemic restrictions slow down, employees start to return to their offices. Hence, the discussions on optimal workplaces and issues of diversity and inclusion have peaked. Previous research has shown that employees and companies benefit from positive workplace changes.
arxiv
The great migration of Bax and Bak [PDF]
Molecular & Cellular Oncology, 2015 The Bcl-2 proteins Bcl-2-associated X protein (Bax) and Bcl-2 antagonist killer 1 (Bak) can commit cells to apoptosis. Retrotranslocation of Bax from the mitochondria into the cytosol is essential for cell survival. Recently, we reported that Bak is also present in the cytosol of healthy cells and that Bax and Bak are regulated by the same ...
openaire +3 more sources
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan +13 more
wiley +1 more source
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the mechanism of lutein on the proliferation and apoptosis of human prostate cancer PC3 cells, and to provide a new theoretical basis for the treatment and prevention of prostate cancer.
WANG Liping +5 more
doaj +1 more source