Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis [PDF]
, 2015 Translocation of the pro-apoptotic protein Bax from the cytosol to the mitochondria is a crucial step in DNA damage-mediated apoptosis, and is also found to be involved in mitochondrial fragmentation.
Andersson +58 more
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Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling [PDF]
, 2013 Pramanicin (PMC) is an antifungal agent that was previously demonstrated to exhibit antiangiogenic and anticancer properties in a few in vitro studies. We initially screened a number of PMC analogs for their cytotoxic effects on HCT116 human colon cancer
Başağa, Hüveyda +5 more
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Креативная хирургия и онкология, 2017 Previously, we designed DTCM-glutarimide as a novel anti-inflammatory agent inhibiting macrophage activation. It also showed anti-inflammatory activity in vivo.
A. Kaneda, Sh. Kh. Gantsev, K. Umezawa
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Effect of aerobic exercise on some factors of cardiac apoptosis in male rats
Fiyz̤, 2019 Background: Cardiac apoptosisplays an important role in myocardial diseases. Current evidence suggests that exercise training may modify some apoptosis-related signaling in myocardium.
Sadighi A +3 more
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Diagnostic Pathology, 2012 Background In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle.
Ozer Hatice +5 more
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Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. [PDF]
, 2017 Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation ...
Chwa, Marilyn +6 more
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Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico +13 more
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Kinetic Study of Reaction between Allyl Compounds of Mg and Ethylene: Computational Investigation [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2017 The reactions of propenyl magnesium halides with ethylene were studied using ab initio calculations. The structure of the transition state and the ground state were evaluated and obtained the structural properties, theoretical thermodynamic and kinetic ...
Elahe Rajaeian, Avat (Arman) Taherpour
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Cleavage in Dutch society : changing patterns of social and economic discrimination [PDF]
The paper considers a (static) portfolio system that satisfies adding-up contraints and the gross substitution theorem. The paper shows the relationship of the two conditions to the weak dominant diagonal property of the matrix of interest rate ...
Bax, E.H.
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HSPB1 alleviates acute-on-chronic liver failure via the P53/Bax pathway
Open Life SciencesThe mortality rate of acute-on-chronic liver failure (ACLF) remains significantly elevated; hence, this study aimed to investigate the impact of heat shock protein family B (small) member 1 (HSPB1) on ACLF in vivo and in vitro and the underlying ...
Zhang Zhixiang, Guo Jinwei, Zhu Jincan
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