Results 41 to 50 of about 767,112 (259)

Inferring a Property of a Large System from a Small Number of Samples

open access: yesEntropy, 2022
Inferring the value of a property of a large stochastic system is a difficult task when the number of samples is insufficient to reliably estimate the probability distribution.
Damián G. Hernández, Inés Samengo
doaj   +1 more source

Bayesian Orgulity [PDF]

open access: yes, 2013
A piece of folklore enjoys some currency among philosophical Bayesians, according to which Bayesian agents that, intuitively speaking, spread their credence over the entire space of available hypotheses are certain to converge to the truth.
Belot, Gordon, Gordon Belot
core   +1 more source

Bayesian Nonparametric Weighted Sampling Inference

open access: yes, 2021
It has historically been a challenge to perform Bayesian inference in a design-based survey context. The present paper develops a Bayesian model for sampling inference in the presence of inverse-probability weights.
Gelman, Andrew   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Parameters and genetic trends for reproductive characteristics of a closed Angus herd

open access: yesRevista Colombiana de Ciencias Pecuarias, 2019
Background: Closed breeding populations are usefull to conduct basic and applied research. The Wye Angus herd is one of them. It was founded using only a few animals.
Vanius B. Falleiro   +5 more
doaj   +1 more source

A surrogate Bayesian framework for a SARS-CoV-2 data driven stochastic model

open access: yesComputational and Mathematical Biophysics, 2022
Dynamic compartmentalized data (DCD) and compartmentalized differential equations (CDEs) are key instruments for modeling transmission of pathogens such as the SARS-CoV-2 virus.
Ganesh M., Hawkins S. C.
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Bayesian threshold analysis of litter size in sheep

open access: yesRevista Colombiana de Ciencias Pecuarias, 2022
Background: Litter size at birth (LSB) is one of the most important economic traits in sheep and could be used in genetic improvement schemes for meat production.
Amin Mortazavi   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

An explanatory differential item functioning (DIF) model by the WinBUG 1.4 [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2007
This study proposed a multilevel logistic regression model to evaluate a source of DIF. The model accounts for the three levels nested structure of the data and combines results of logistic regression analysesto identify level-3 unit characteristic ...
Fred W. Huffer   +2 more
doaj  

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