Results 51 to 60 of about 341,773 (269)
Frontiers in Environmental Science, 2021 Large compilations of heterogeneous environmental observations are increasingly available as public databases, allowing researchers to test hypotheses across datasets.
Gregory L. Britten +13 more
doaj +1 more source
Bayesian and non-bayesian evidential updating
Artificial Intelligence, 1987 Orthodox probability theory supposes that (1) we commence with known statistical distributions, (2) these distributions give rise to real- valued probabilities, and (3) these probabilities can be updated by the use of Bayes' theorem. Each of these suppositions has been challenged by recent work in computer science concerning the representation and ...
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An explanatory differential item functioning (DIF) model by the WinBUG 1.4 [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2007 This study proposed a multilevel logistic regression model to evaluate a source of DIF. The model accounts for the three levels nested structure of the data and combines results of logistic regression analysesto identify level-3 unit characteristic ...
Fred W. Huffer +2 more
doaj
Psychologica Belgica, 2021 Mixed results of the impact of transcranial direct current stimulation (tDCS) on working memory have been reported. Contrarily to previous studies who focused mainly on stimulating the dorsolateral prefrontal cortex, we modulated the left intraparietal ...
Romain Dumont +2 more
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Probabilistic optimization in the human perceptuo-motor system
Journal of Physical Fitness and Sports Medicine, 2013 Despite the variability of internal and external environments, the human central nervous system (CNS) can generate precise and stable perception and motor behaviors. What mechanism enables this ability?
Shigeki Takeuchi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Modeling forest bird population trends at U.S. Army Garrison Pōhakuloa Training Area, Hawaiʻi
Avian Conservation and EcologyHawaiian avifaunal communities have suffered irrevocable harm and significant threats remain for extant species. It is increasingly important to monitor and document bird density to improve our understanding of how remaining species respond to changing ...
Brian T Leo, Lena D Schnell
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