Results 51 to 60 of about 154,626 (299)

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

On the degeneration of étale $\Bbb Z/p\Bbb Z$ and $\Bbb Z/p^2\Bbb Z$-torsors in equal characteristic $p>0$

Hiroshima Mathematical Journal, 2007
Let $R$ be a complete discrete valuation ring of equal characteristic $p>0$. In this paper we investigate finite and flat morphisms $f:Y\to X$ between formal $R$-schemes which have the structure of an etale $\Bbb Z/p^n\Bbb Z$-torsor above the generic fiber of $X$, for $n=1,2$, with some extra geometric conditions on $X$ and $Y$.
openaire   +2 more sources

Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders

Molecular Brain, 2022
The integrity of the blood–brain barrier (BBB) is essential for normal central nervous system (CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the neural environment, we aim to provide an overview of significant ...
Hema Kumari Alajangi, Mandeep Kaur, Akanksha Sharma, Sumedh Rana, Shipali Thakur, Mary Chatterjee, Neha Singla, Pradeep Kumar Jaiswal, Gurpal Singh, Ravi Pratap Barnwal   +9 more
doaj   +1 more source

Homomorphic images of $\Bbb R$-factorizable groups

, 2006
summary:It is well known that every $\Bbb R$-factorizable group is $\omega $-narrow, but not vice versa. One of the main problems regarding $\Bbb R$-factorizable groups is whether this class of groups is closed under taking continuous homomorphic images ...
Tkachenko, M.
core   +1 more source

BBB endothelial signature genes.

, 2013
BBB endothelial signature genes.
Roberta Paolinelli (237864), Eleanna Papa (441409), Cédric Artus (441405), Stefan Liebner (307398), Elisabetta Dejana (110746), Pierre Olivier Couraud (383879), Noemi Rudini (441407), Monica Corada (217515), Cathrin J. Czupalla (441406), Luca Ferrarini (441403), Luigi Maddaluno (441408), Britta Engelhardt (307404), Kavi Devraj (441404)   +12 more
core   +1 more source

BBB leakage assessment.

, 2021
In order to confirm that blood-brain barrier leakage was not a confound in our experiment, we later assessed available APOE4 rats (n = 5) that were slightly older (16 months) and on a high fat diet- both of which would exacerbate BBB leakage if present. (
Marc D. Normandin (1583074), Dharshan Chandramohan (11348926), Ju Qiao (6004292), Anne L. van de Ven (11348929), Liam Timms (11348932), Craig F. Ferris (7123448), Georges El Fakhri (520533), Codi Gharagouzloo (11348935), Jorge Sepulcre (81907), Praveen Kulkarni (433608), Chao Ma (207385), Joshua Leaston (11348923)   +11 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Binary sequences which contain no $BBb$ [PDF]

Transactions of the American Mathematical Society, 1980
A (one-sided) sequence or (two-sided) bisequence is irreducible provided it contains no block of the form BBb, where b is the initial symbol of the block B. Gottschalk and Hedlund [Proc. Amer. Math. Soc. 15 (1964), 70-74] proved that the set of irreducible binary bisequences is the Morse minimal set M. Let M+ denote the one-sided Morse minimal set, i.e.
openaire   +2 more sources

Subgroups of $\Bbb R$-factorizable groups

, 1998
summary:The properties of $\Bbb R$-factorizable groups and their subgroups are studied. We show that a locally compact group $G$ is $\Bbb R$-factorizable if and only if $G$ is $\sigma$-compact. It is proved that a subgroup $H$ of an $\Bbb R$-factorizable
Tkačenko, Michael, Hernández, Constancio   +1 more
core   +1 more source

Mechanisms of Astrocyte Action in the Blood Brain Barrier: From Structural Support to Dynamic Regulation

Journal of Integrative Neuroscience
The blood-brain barrier (BBB) consists of endothelial cells enmeshed by brain microvessels, surrounding basement membrane, pericytes and astrocyte pedicles.
Di Feng, Lili Wang, Aoyu Hu, Shanshan Zhang   +3 more
doaj   +1 more source