Results 61 to 70 of about 154,626 (299)
“Build back better” approach to disaster recovery: Research trends since 2006
Progress in Disaster Science, 2019 The “build back better” (BBB) approach to disaster recovery was first introduced in 2006 by the United Nations Secretary-General's Special Envoy for Tsunami Recovery, former US President William Clinton.
Glenn Fernandez, Iftekhar Ahmed
doaj +1 more source
Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma. [PDF]
Adv Sci (Weinh)Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Paul AR +4 more
europepmc +2 more sources
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
What “Hides” Behind Sovereign Debt Ratings? [PDF]
In this paper we study the determinants of sovereign debt credit ratings using rating notations from the three main international rating agencies, for the period 1995-2005. We employ panel estimation and random effects ordered probit approaches to assess
António Afonso +2 more
core +2 more sources
Brain Pericytes — Crucial Regulators of Neuroinflammation in Ischemic Stroke
Neuropharmacology and TherapyInflammation is a key element in the pathophysiology of ischemic stroke. The current effective treatments for ischemic stroke are almost exclusively based on reperfusion of occluded vessels.
Ziyi Chen +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Ensemble Predictions for TDC BBB-Martins Leaderboard
, 2023 Ensemble predictions for a drugs ability to penetrate the blood brain barrier using Therapeutic Data Commons BBB-Martins dataset. Includes .tsv files with the actual and predicted classifications of BBB permeability for each drug in the TDC test set ...
Rick Fontenot (14855842)
core +1 more source
Advanced Healthcare Materials, EarlyView.Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu +5 more
wiley +1 more source
Inhibition of RIPK1 activity retarded BBB leakage.
, 2023 (A). The measurement of permeability of the BBB in wild-type and Ripk1D138N mutant mice. (B). The quantifications of fluorescence intensity of p-RIPK1 and leaked IgG during CIRI.
Yongjiao Wang (2192470) +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li +9 more
wiley +1 more source