Results 31 to 40 of about 272,441 (303)

Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood − brain barrier function

Fluids and Barriers of the CNS, 2023
Autoreactive T lymphocytes crossing the blood-brain barrier (BBB) into the central nervous system (CNS) play a crucial role in the initiation of demyelination and neurodegeneration in multiple sclerosis (MS).
Baharak Hosseinkhani, Gayel Duran, Cindy Hoeks, Doryssa Hermans, Melissa Schepers, Paulien Baeten, Joren Poelmans, Britt Coenen, Kübra Bekar, Isabel Pintelon, Jean-Pierre Timmermans, Tim Vanmierlo, Luc Michiels, Niels Hellings, Bieke Broux   +14 more
doaj   +1 more source

Entire curves avoiding given sets in C^n

, 2003
Let $F\subset\Bbb C^n$ be a proper closed subset of $\Bbb C^n$ and $A\subset\Bbb C^n\setminus F$ at most countable ($n\geq 2$). We give conditions of $F$ and $A$, under which there exists a holomorphic immersion (or a proper holomorphic embedding) $\phi:\
B. Drinovec Drnovšek, C. Catlin, D. Varolin, F. Forstnerič, F. Forstnerič, J.-P. Rosay, J.-P. Rosay, J.-P. Rosay, N. Nikolov, Nikolai Nikolov, P. M. Gauthier, Peter Pflug, R. C. Gunning, T. Ueda, W. Jarnicki   +14 more
core   +1 more source

On equivariant characteristic ideals of real classes

, 2013
Let $p$ be an odd prime, $F/{\Bbb Q}$ an abelian totally real number field, $F_\infty/F$ its cyclotomic ${\Bbb Z}_p$-extension, $G_\infty = Gal (F_\infty / {\Bbb Q}),$ ${\Bbb A} = {\Bbb Z}_p [[G_\infty]].$ We give an explicit description of the ...
A. Huber, A. Nickel, A. Nickel, B. Mazur, C. Greither, C. Weibel, D. Burns, D. Burns, J. Ritter, J. Ritter, M. Flach, M. Witte, P. Schneider, T. Beliaeva, V.P. Snaith   +14 more
core   +1 more source

Treatment with penicillin G and hydrocortisone reduces ALS-associated symptoms: a case series of three patients [version 1; referees: 2 approved]

F1000Research, 2017
Three male Caucasian patients with ALS were admitted to the hospital due to progressive dysphagia and dysarthria. During two 21-day courses of penicillin G and hydrocortisone, these patients’ dysphagia and dysarthria resolved.
Bert Tuk, Harmen Jousma, Pieter J. Gaillard   +2 more
doaj   +1 more source

On the dynamics of WKB wave functions whose phase are weak KAM solutions of H-J equation

, 2013
In the framework of toroidal Pseudodifferential operators on the flat torus $\Bbb T^n := (\Bbb R / 2\pi \Bbb Z)^n$ we begin by proving the closure under composition for the class of Weyl operators $\mathrm{Op}^w_\hbar(b)$ with simbols $b \in S^m (\mathbb{
A Fathi, A Martinez, G Contreras, G Folland, JJ Duistermaat, JN Mather, L Ambrosio, L Ambrosio, L Ambrosio, L Ambrosio, L Hörmander, LC Evans, LC Evans, LC Evans, Lorenzo Zanelli, M Ruzhansky, MG Crandall, P Bernard, P Gérard, P-L Lions, P-L Lions, PL Lions, R Manè, S Graffi, Thierry Paul, X Yang   +25 more
core   +2 more sources

review on the role of nanoparticles for targeted brain drug delivery

EXCLI Journal : Experimental and Clinical Sciences
Unfortunately, nowadays, brain disorders, which include both neurological and mental disorders, are the main cause of years spent living with a disability worldwide. There are serious diseases with a high prevalence and a high mortality rate.
Payam Nawzad Mohammed, Narmin Hamaamin Hussen, Aso Hameed Hasan, Hozan Jaza Hama Salh, Joazaizulfazli Jamalis, Sumeer Ahmed, Ajmal R. Bhat, Mohammad Amjad Kamal   +7 more
doaj   +1 more source

Dynamic Interleukin-1 Receptor Type 1 Signaling Mediates Microglia-Vasculature Interactions Following Repeated Systemic LPS

Journal of Inflammation Research, 2022
Daniel P Nemeth,1– 3 Xiaoyu Liu,3 Daniel B McKim,4 Damon J DiSabato,2,5 Braedan Oliver,2 Anu Herd,3 Asish Katta,1 Christina E Negray,1,2 James Floyd,3 Samantha McGovern,3 Paige S Pruden,2 Feiyang Zhutang,2 Maria Smirnova,3 Jonathan P Godbout,2,5 John ...
Nemeth DP, Liu X, McKim DB, DiSabato DJ, Oliver B, Herd A, Katta A, Negray CE, Floyd J, McGovern S, Pruden PS, Zhutang F, Smirnova M, Godbout JP, Sheridan JF, Quan N   +15 more
doaj  

Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier

Advanced Science, 2021
The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from entering the brain.
Jia Li, Meng Zheng, Olga Shimoni, William A. Banks, Ashley I. Bush, Jennifer R. Gamble, Bingyang Shi   +6 more
doaj   +1 more source

Hankel and Toeplitz operators: continuous and discrete representations

, 2016
We find a relation guaranteeing that Hankel operators realized in the space of sequences $\ell^2 ({\Bbb Z}_{+}) $ and in the space of functions $L^2 ({\Bbb R}_{+}) $ are unitarily equivalent.
Yafaev, D. R.
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source