Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle [PDF]
, 2006 Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
Hope, J C, Howard, C J, Sopp, P
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Radiology and Oncology, 2020 Bladder cancer is the 7th most common cancer in men. About 75% of all bladder cancer are non-muscle invasive (NMIBC). The golden standard for definite diagnosis and first-line treatment of NMIBC is transurethral resection of bladder tumour (TURB ...
Taskovska Milena +2 more
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B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response [PDF]
, 2013 We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection. The present study examined the mechanisms by
A Casadevall +74 more
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Serendipity and strategy in rapid innovation
Nature Communications, 2017 Organizations can take different approaches to innovation: they can either follow a strategic process or a serendipitous perspective. Here Fink et al. develop a statistical model to analyse how components combine to obtain a product and thus explain the ...
T. M. A. Fink +3 more
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A rapid review of recent advances in diagnosis, treatment and vaccination for COVID-19
AIMS Public Health, 2021 COVID-19 is caused by SARS-CoV-2, which originated in Wuhan, Hubei province, Central China, in December 2019 and since then has spread rapidly, resulting in a severe pandemic.
Srikanth Umakanthan +5 more
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Effect of Hypertension on Outcomes of High-Risk Patients After BCG-Treated Bladder Cancer [PDF]
, 2015 Immunotherapy with Bacillus Calmette Guerin (BCG) is the most efficacious treatment for high-risk bladder cancer (BC) (Ta/T1 or carcinoma in situ) to reduce the risk of recurrence.
Alberto, Bovo +5 more
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Penta is associated with an increased female-male mortality ratio: cohort study from Bangladesh
Human Vaccines & Immunotherapeutics, 2021 Diphtheria-tetanus-pertussis (DTP) vaccine may be associated with excess female deaths. There are few studies of possible nonspecific effects of the DTP-containing vaccine Penta (DTP-hepatitis B-Haemophilus influenzae type b).
Syed Manzoor Ahmed Hanifi +4 more
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PO and ID BCG vaccination in humans induce distinct mucosal and systemic immune responses and CD4(+) T cell transcriptomal molecular signatures. [PDF]
, 2017 Protective efficacy of Bacillus Calmette-Guérin (BCG) may be affected by the methods and routes of vaccine administration. We have studied the safety and immunogenicity of oral (PO) and/or intradermal (ID) administration of BCG in healthy human subjects.
Andersen, P. L. +11 more
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Bacille Calmette–Guérin (BCG) Vaccine Induced Tuberculous Lymphadenitis: A Case Report
Journal of Nobel Medical College, 2020 Bacille Calmette-Guérin lymphadenitis is one of the most common complication of this vaccination. We present a case report of infant with this vaccination induced lymphadenitis treated successfully with anti-tubercular therapy.
Kalyan Sapkota
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BCG: a vaccine with multiple faces
Human Vaccines & Immunotherapeutics, 2020 BCG has been recommended because of its efficacy against disseminated and meningeal tuberculosis. The BCG vaccine has other mechanisms of action besides tuberculosis protection, with immunomodulatory properties that are now being discovered. Reports have
Marco Antonio Yamazaki-Nakashimada +4 more
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