Results 121 to 130 of about 806,785 (277)
Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi. [PDF]
, 2001 SETTING: Rural northern Malawi, where vaccination with BCG Glaxo (1077) provides protection against leprosy but not against pulmonary tuberculosis. OBJECTIVE: To evaluate the patterns of responsiveness to purified protein derivative of Mycobacterium ...
Fine PEM +12 more
core +2 more sources
Outcomes of controlled human malaria infection after BCG vaccination
Nature Communications, 2019 Recent evidence suggests that certain vaccines, including Bacillus-Calmette Guérin (BCG), can induce changes in the innate immune system with non-specific memory characteristics, termed ‘trained immunity’.
J. Walk +19 more
semanticscholar +1 more source
“Trained immunity” from Mycobacterium spp. exposure or BCG vaccination and COVID-19 outcomes
medRxiv, 2020 Protective variables for COVID-19 are unknown. 'Trained immunity' of the populace as a result of BCG policy implementation and coverage had been suggested to be one of the factors responsible for the differential impact of COVID-19 on different countries.
Samer Singh, R. P. Maurya, R. Singh
semanticscholar +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, Volume 115, Issue 11, Page 2433-2440, November 2026.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Immune System Development—Pro Tips for Paediatricians
Acta Paediatrica, Volume 115, Issue 11, Page 2398-2401, November 2026.ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley +1 more source
COVID-19 and BCG vaccine: is there a link?
Инфекция и иммунитет, 2020 The spread of the novel coronavirus infection (COVID-19) makes the search for new approaches to prevent the infection of great importance. As one of the relevant approaches, the vaccination of risk groups with BCG vaccine has recently been suggested. BCG
I. V. Lyadova, A. A. Starikov
doaj +1 more source
A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA
Acta Paediatrica, Volume 115, Issue 11, Page 2498-2504, November 2026.ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley +1 more source
A Breath of Fresh Air: BCG Prevents Adult Pulmonary Tuberculosis
International Journal of Infectious Diseases, 2019 Objectives: The efficacy of childhood BCG vaccination in the prevention of adult pulmonary tuberculosis is not universally accepted. Methods: We reviewed the published literature and summarized studies of BCG vaccination reporting long-term protection ...
David de Gijsel, C. Fordham von Reyn
doaj +1 more source
Journal of Immunology Research, 2020 BCG vaccination protects not only against tuberculosis but also against heterologous infections. This effect differs between individuals, yet the factors responsible for this variation are unknown.
Vera P. Mourits +11 more
doaj +1 more source
The Humoral Immune Response to BCG Vaccination
Frontiers in Immunology, 2019 Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis (TB), but it confers incomplete and variable protection against pulmonary TB in humans and bovine TB (bTB) in cattle. Insights into the immune response induced by
R. Tanner +3 more
semanticscholar +1 more source