Results 131 to 140 of about 806,785 (277)

Trained Immunity in Childhood Vaccination

Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]

, 2011
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
core   +1 more source

BCG Vaccination and Tuberculosis in Japan.

Journal of Epidemiology, 2003
This paper summarizes Bacillus Calmette-Guerin (BCG) vaccination and revaccination policies in Japan, its cost-effectiveness, side effects, proposed selective vaccination strategy, and present tuberculosis situation in Japanese perspectives based on Medline database and other published reports.
Rahman, Mahbubur, Takahashi, Osamu, Goto, Masashi, Fukui, Tsuguya   +3 more
openaire   +3 more sources

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, Volume 78, Issue 10, Page 1510-1521, October 2026.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

The impact of HIV exposure and maternal Mycobacterium tuberculosis infection on infant immune responses to bacille Calmette-Guérin vaccination. [PDF]

, 2015
OBJECTIVE: The objective of this study is to assess the effect of maternal HIV and Mycobacterium tuberculosis (Mtb) infection on cellular responses to bacille Calmette-Guérin (BCG) immunization. DESIGN: A mother-infant cohort study.
Kampmann, B, Martin Kidd, Wilkinson, Robert J, Robert J. Wilkinson, Kidd, M, Jones, Christine E, Tena-Coki, Nontobeko G, Scriba, Thomas J, Hesseling, AC, Thomas J. Scriba, Jones, Christine E., Tena-Coki, Nontobeko G., Kampmann, Beate, Christine E. Jones, Wilkinson, Robert J., Nontobeko G. Tena-Coki, Tena-Coki, NG, Scriba, Thomas J., Chegou, Novel N., Chegou, NN, Scriba, TJ, Anneke C. Hesseling, Wilkinson, RJ, Hesseling, Anneke C, Jones, CE, Novel N. Chegou, Beate Kampmann, Chegou, Novel N, Hesseling, Anneke C., Kidd, Martin   +29 more
core   +1 more source

BCG vaccination is associated with longitudinal changes in systemic eicosanoid levels in elderly individuals: A secondary outcome analysis

Heliyon
We investigated how BCG vaccination affects the levels of certain eicosanoids, namely Leukotriene B4, 15-epimer of LXA4, prostaglandin F2, Lipoxin A4, Prostaglandin E2 and Resolvin D1 in the plasma of healthy elderly individuals (aged 60–80) before ...
Pavan Kumar Nathella, Chandrasekaran Padmapriyadarsini, Arul Nancy, Kushiyasri Karunanithi, Nandhini Selvaraj, Rachel Mariam Renji, B.M. Shrinivasa, Subash Babu   +7 more
doaj   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, Volume 38, Issue 56, 8 October 2026.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, Volume 13, Issue 59, 23 October 2026.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity [PDF]

, 2012
© 2012 Elsevier Ltd. All rights reservedBackground: The development of a new, more effective vaccine against tuberculosis (TB) for use in healthy and HIV-infected adults, children and infants, remains a global health priority.
Sander, C, Angela M Minassian, Nicola Williams, Lawrie, AM, Alison M Lawrie, Rowland, R, Poulton, ID, Rosalind Rowland, Brittain, N, Pathan, AA, David W Porter, Minassian, AM, Helen McShane, Iman Satti, Ansar A Pathan, Ian D Poulton, Nathaniel Brittain, Williams, N, Clare Sander, Porter, DW, Satti, I, McShane, H   +21 more
core   +1 more source

The Effect of Stress, BCG Vaccination,and Combination of Stress-BCG Vaccination to The Ability of Macrophage to Bind with CD4+ T Cells in BALB/c Mice [PDF]

, 2006
The Effect of Stress, BCG Vaccination,and Combination of Stress-BCG Vaccination to The Ability of Macrophage to Bind with CD4+ T Cells in BALB/c Mice Rahajeng N. Tunjung*, Dwi Pudjonarko** Background.
Tunjung, Rahajeng_N.
core   +1 more source