Results 151 to 160 of about 806,785 (277)

Maturation‐Dependent Constraints in the Ability of Human Monocytes to Initiate Trained Immunity

MedComm, Volume 7, Issue 10, October 2026.
In premature infants, innate immune memory may serve as an important compensatory mechanism for the underdeveloped adaptive immune system. However, monocytes derived from prematurely born individuals display abnormal metabolic and insufficient transcriptomic responses to β‐glucan‐induced training.
Michael Eigenschink, Elsa Davogg, Manuel Pristner, David Seki, Marcus Arzmüller, Herbert Kiss, Alex Farr, Angelika Berger, David Berry, Benedikt Warth, Lukas Wisgrill   +10 more
wiley   +1 more source

Cholesterol 25‐Hydroxylase Deficiency Provides an Optimal and Durable Protective T Helper 1 Immunity via Interleukin‐12–Interleukin‐2 Axis in BCG‐Vaccinated Mice

MedComm, Volume 7, Issue 10, October 2026.
CH25H deficiency permits optimal dendritic cell activation following BCG exposure, characterized by increased IL‐12p70 production. In vivo, CH25H deficiency promotes enhanced BCG‐mediated protection and sustained IL‐2 producing T cell response. ABSTRACT Bacillus Calmette‐Guérin (BCG) remains the only licensed vaccine for tuberculosis (TB), yet its ...
Hagyu Kim, Eunsol Choi, Kee Woong Kwon, Hong‐Hee Choi, Kyungmin Kim, WeonSeok Jung, Sung Jae Shin   +6 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

BCG Vaccination-Associated Lower HbA1c and Increased CD25 Expression on CD8⁺ T Cells in Patients with Type 1 Diabetes in Ghana

Vaccines
BCG vaccination affects other diseases beyond tuberculosis by unknown—potentially immunomodulatory—mechanisms. Recent studies have shown that BCG vaccination administered during overt type 1 diabetes (T1D) improved glycemic control and affected immune ...
Wilfred Aniagyei, Sumaya Mohayideen, Osei Sarfo-Kantanka, Sarah Bittner, Monika M. Vivekanandan, Joseph F. Arthur, Agnes O. Boateng, Augustine Yeboah, Hubert S. Ahor, Shadrack O. Asibey, Elizabeth Owusu, Diran Herebian, Maximilian Huttasch, Volker Burkart, Robert Wagner, Michael Roden, Ernest Adankwah, Dorcas O. Owusu, Ertan Mayatepek, Marc Jacobsen, Richard O. Phillips, Julia Seyfarth   +21 more
doaj   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang, Ruomeng Li, Chuanjiang Yu, Jing Li, Xikun Zhou   +4 more
wiley   +1 more source

[BCG vaccination in the world].

Kekkaku : [Tuberculosis], 2000
BCG vaccination programme and BCG vaccination coverage in the world were summarized mainly based on the published informations from official organizations, such as World Health Organization (WHO), International Union Against Tuberculosis and Lung Disease (IUATLD) and Centers for Disease Control and Prevention (CDC).
openaire   +2 more sources

Impact of Central Asia Stunting Initiative on Stunting and Anemia Among Children and Women of Afghanistan

Maternal &Child Nutrition, Volume 22, Issue 4, October 2026.
ABSTRACT The Central Asia Stunting Initiative (CASI) is a program designed to address malnutrition among women of reproductive age and children under five in Badakhshan Province, Afghanistan, a region facing significant nutritional challenges. This study used a pre‐post design to assess the impact of CASI interventions, with cross‐sectional surveys ...
Imran A. Chauhadry, Aminah Jahangir, Muhammad Umer, Khakerah Rashidi, Habibullah Haziq, Rafi Sadeed, Humayun Helal, Muhammad Atif Habib, Imtiaz Hussain, Shabina Ariff, Tatyana Elkour, Sajid B. Soofi, Claudia Hudspeth, Zulfiqar A. Bhuuta   +13 more
wiley   +1 more source

Association of early life anti‐pathogen immune responses with infant food sensitisation and allergy: An elastic‐net stability‐selection approach

Pediatric Allergy and Immunology, Volume 37, Issue 10, October 2026.
Stability selection using penalised regression was applied to cytokine responses in microbially stimulated whole blood samples collected at 6 months, together with clinical factors, to identify associations with food sensitisation and food allergy at 1 year.
Ellie McDonald, Sofie Biering‐Sørensen, Laure F. Pittet, Nigel Curtis, Nicole L. Messina   +4 more
wiley   +1 more source

Immune responses of cattle vaccinated by various routes with Mycobacterium bovis Bacillus Calmette-Guérin (BCG)

BMC Veterinary Research
Background Mycobacterium bovis BCG is the human tuberculosis vaccine and is the oldest vaccine still in use today with over 4 billion people vaccinated since 1921.
Mitchell V. Palmer, Soyoun Hwang, Carly Kanipe, Ellie J. Putz, Luis Guilherme Virgilio Fernandes, Anna Didkowska, Paola M. Boggiatto   +6 more
doaj   +1 more source

Interferon-gamma and skin test responses of schoolchildren in southeast England to purified protein derivatives from Mycobacterium tuberculosis and other species of mycobacteria.

, 2003
The immune responses of schoolchildren in southeast England to Mycobacterium tuberculosis and other species of mycobacteria were studied prior to vaccination with bacille Calmette-Guérin (BCG).
Branson, K, King, E, Dockrell, HM, Black, GF, Weir, RE, Bliss, L, Fine, PEM, Nazareth, B, Stanley, C, Floyd, S   +9 more
core   +1 more source