Results 41 to 50 of about 219,243 (185)

FOXP3 interacts with hnRNPF to modulate pre-mRNA alternative splicing [PDF]

, 2018
FOXP3 promotes the development and function of regulatory T cells mainly through regulating the transcription of target genes. RNA alternative splicing has been implicated in a wide range of physiological and pathophysiological processes.
Du, Jianguang, Wang, Qun, Zhou, Baohua, Ziegler, Steven F.   +3 more
core   +1 more source

Reproductive status of male rat offspring following exposure to methamphetamine during intrauterine life: An experimental study

International Journal of Reproductive BioMedicine, 2023
Background: Methamphetamine abuse during pregnancy is associated with maternal and fetal adverse outcomes. Methamphetamine induces reproductive damage in adults; however, its effect has not been studied during pregnancy.
Zahra Khoshgoftar Some Saraii, Soroush Dianaty, Fatemeh Rouhollah, Nayereh Zare, Batool Ghorbani Yekta   +4 more
doaj   +1 more source

How to target apoptosis signaling pathways for the treatment of pediatric cancers [PDF]

, 2013
Apoptosis represents one of the most important forms of cell death in higher organisms and is typically dysregulated in human cancers, including pediatric tumors.
Fulda, Simone
core   +2 more sources

Impact of neurotrophic factors combination therapy on retinitis pigmentosa

Journal of International Medical Research, 2020
Objective We aimed to determine the location of neurotrophic receptors tropomyosin receptor kinase (Trk)B, TrkC, and ciliary neurotrophic factor receptor (CNTFR)α in the retina of retinal degeneration ( rd ) mice and to explore the dynamic changes of B ...
Xiaobei Yin, Ting He, Rui Chen, Hui Cui, Genlin Li   +4 more
doaj   +1 more source

Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]

, 2016
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano, Gatla, Himavanth, Vancura, Ales, Vancurova, Ivana   +3 more
core   +2 more sources

The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections

Virulence, 2019
Virus infection induces different cellular responses in infected cells. These include cellular stress responses like autophagy and unfolded protein response (UPR).
Parvaneh Mehrbod, Sudharsana R. Ande, Javad Alizadeh, Shahrzad Rahimizadeh, Aryana Shariati, Hadis Malek, Mohammad Hashemi, Kathleen K. M. Glover, Affan A. Sher, Kevin M. Coombs, Saeid Ghavami   +10 more
doaj   +1 more source

Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Renal and testicular disorders are primarily associated with oxidative damage and inflammation. Here, alpha-pinene (a type of monoterpene) was investigated for its effect on oxidative/nitrosative stress and the expression of inflammatory ...
Fatemeh Noroozi, Masoumeh Asle Rousta, Rahim Amini, Zeinab Sahraeian   +3 more
doaj   +1 more source

Cytotoxic effects of curcumin on osteosarcoma cell lines [PDF]

, 2018
Summary: Curcumin (diferuloylmethane), one of the main components of the Indian spice turmeric, is known to possess potent anti-inflammatory and anti-oxidant properties.
Born, Walter, Fuchs, Bruno, Langsam, Bettina, Muff, Roman, Walters, Denise   +4 more
core   +1 more source

Dissecting the pathways of tumour escape: " question of life and death?" Dissecando os caminhos de escape do tumor: "uma questão de vida e morte?"

Anais Brasileiros de Dermatologia, 2010
Apoptotic pathways are providing important saveguard mechanisms in protection from cancer by eliminating altered and often harmful cells. The disturbances of cell proliferation, differentiation and apoptosis are also found on specific signal-transduction
Georgi Tchernev, Pietro Nenoff
doaj   +1 more source

The simultaneous effect of valproic acid and gamma radiation on telomerase activity and bax and Bcl-2 protein levels in MCF-7 breast cancer cell line [PDF]

, 2015
Background: Breast cancer is one of the most prevalent types of cancer. Factors such as ionizing radiation and chemotherapeutic agents can trigger apoptosis and cancer cell death.
Asadi, J., Binabaj, M.M., Hosseini, S.A., Khoshnazar, A.K.   +3 more
core   +1 more source