Results 111 to 120 of about 21,951,536 (341)

Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells. [PDF]

, 1987
W. Graninger, M Seto, B Boutain, P Goldman, S J Korsmeyer   +4 more
openalex   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Simultaneous presentation of T- and B-cell malignant lymphoma with bcl- 2 gene involvement [PDF]

, 1989
FE Cotter, PA Hall, BD Young, TA Lister
openalex   +1 more source

Bcl-2 family members and disease

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004
Apoptosis plays an important role during development and in the maintenance of multicellular organisms. Bcl-2 family members affect cell death in either a positive or negative fashion. Although some redundancy exists between family members, expression of certain family members is important during development in an organ-specific manner.
openaire   +2 more sources

In Situ Monitoring and Electrical Modulation of Cellular Behaviors Directly at the Cell–Electrode Interface

Advanced Materials Interfaces, EarlyView.
This study presents a platform for simultaneous monitoring and electrical control of cellular responses at the cell–electrode interface. The platform delivers tunable yet uniform electrical cues to cells, revealing that optimal electrical stimulation (ES) conditions vary across cell types.
Khandoker Asiqur Rahaman, Yeon Jae Chang, Hyeok Kim, Tae Kyoung Lee, Jaeyeon Jun, Min Jung Kim, Jimin Park, Hyung‐Seop Han   +7 more
wiley   +1 more source

Loss of Heterozygosity at the bcl‐2 Gene Locus and Expression of bcl‐2 in Human Gastric and Colorectal Carcinomas [PDF]

, 1994
A. Ayhan, Wataru Yasui, Hiroshi Yokozaki, Masao Seto, Ryuzo Ueda, Eiichi Tahara   +5 more
openalex   +1 more source

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

Journal of Experimental Medicine, 1995
A critical event during programmed cell death (PCD) appears to be the acquisition of plasma membrane (PM) changes that allows phagocytes to recognize and engulf these cells before they rupture.
S. Martin, Chris P. M. Reutelingsperger, A. Mcgahon, James A. Rader, R. V. van Schie, D. Laface, Douglas Tl Green   +6 more
semanticscholar   +1 more source

Liquiritin Exerts a Dual Effect on BMSCs Osteogenic Differentiation and Fracture Healing by Activating the ERK/JNK Pathway and Providing Antioxidant Protection

Advanced Therapeutics, EarlyView.
Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.
Haijun Mao, Jing Liu, Juan Feng, Yalikun Yusufu, Lei Yang, Qing Jiang, Minghui Sun   +6 more
wiley   +1 more source

H‐2^Z Homozygous New Zealand Mice as a Model for B‐Cell Chronic Lymphocytic Leukemia: Elevated bcl‐2 Expression in CD5 B Cells at Premalignant and Malignant Stages [PDF]

, 1993
Hiroshi Okamoto, Hiroyuki Nishimura, A. Shinozaki, Danqing Zhang, Sachiko Hirose, Toshikazu Shirai   +5 more
openalex   +1 more source

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.

Cancer Research, 2008
Overexpression of the prosurvival Bcl-2 family members (Bcl-2, Bcl-xL, and Mcl-1) is commonly associated with tumor maintenance, progression, and chemoresistance.
Chris Tse, A. Shoemaker, Jessica Adickes, Mark G. Anderson, Jun Chen, Sha S. Jin, Eric F. Johnson, K. Marsh, M. Mitten, Paul M Nimmer, Lisa R. Roberts, S. Tahir, Yu Xiao, Xiufen Yang, Haichao Zhang, S. Fesik, S. Rosenberg, S. Elmore   +17 more
semanticscholar   +1 more source