Results 251 to 260 of about 408,548 (333)
Activator of apoptosis harakiri (HRK) localisation at mitochondria alters mitochondrial morphology independently of other BCL-2 proteins. [PDF]
King LE, Faber L, García-Sáez AJ.
europepmc +1 more source
Impact of organic pollutants on phenotype and gene expression in human breast cancer cells
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin +7 more
wiley +1 more source
Inhibition of antiapoptotic BCL-2 proteins with Lipo-NPs induces fibroblast apoptosis, alleviating pulmonary fibrosis in VILI mice. [PDF]
Yu Q +5 more
europepmc +1 more source
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
<i>In silico</i> evaluation of vitamin D3 as a dual inhibitor of CDK2 and Bcl-2 in colorectal cancer. [PDF]
Shobahah J +4 more
europepmc +1 more source
Discovery of New Pyrazole‐Tosylamide Derivatives as Apoptosis Inducers Through BCL‐2 Inhibition and Caspase‐3 Activation [PDF]
Burak Kuzu, Ege Arzuk
openalex +1 more source
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common non‐Hodgkin lymphoma and is an aggressive and highly heterogeneous tumor. Kaempferitrin (KPF) is a natural flavonoid glycoside that exerts a protective role in multiple human tumors. However, the impact of KPF on DLBCL remains unclear.
Han‐Shuo Zhang +3 more
wiley +1 more source
Immunocytochemical Detection of BCL-2 Protein in Chronic B-Cell Lymphoproliferative Disorders. [PDF]
Abass AE +7 more
europepmc +1 more source
ABSTRACT Hepatocellular carcinoma (HCC) is a heterogeneous malignancy characterized by high mortality rates. This article presents a discussion of the role of ZNF652 in HCC cell proliferation and apoptosis, thereby identifying a new target for HCC treatment. The expression levels of ZNF652, circRHOT1, and SLC38A6 in HCC and healthy cells were analyzed.
Kang Chen +7 more
wiley +1 more source

