Results 211 to 220 of about 45,247 (265)
Advanced Healthcare Materials, Volume 14, Issue 15, 10 June, 2025.A dual‐functional hafnium oxide nanoplatform is developed for enhanced cancer radiotherapy. This innovative system combines the inherent radiosensitizing properties of high‐Z hafnium oxide with Bcl‐2 gene‐silencing capabilities. The nanoplatform demonstrated synergistic enhancement of radiotherapy efficacy through increased generation of reactive ...
Seungyong Shin +12 more
wiley +1 more source
TP53 ‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management
American Journal of Hematology, Volume 100, Issue S4, Page 88-115, June 2025.ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53 mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah +2 more
wiley +1 more source
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, Volume 100, Issue S4, Page 30-50, June 2025.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 3, Page 1942-1955, June 2025.Abstract Aims Patients with cardiomyopathies are a heterogeneous group of patients who experience high morbidity and mortality. Early cardiac assessment and intervention with access to genetic counselling in a multidisciplinary Cardiomyopathy Clinic may improve outcomes and prevent progression to advanced heart failure.
Chandu Sadasivan +12 more
wiley +1 more source
Keratinocyte Apoptosis Induced by Ultraviolet B Radiation and CD95 Ligation – Differential Protection through Epidermal Growth Factor Receptor Activation and Bcl-xL Expression [PDF]
, 2001 Monika Jost +3 more
openalex +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.Melanoma is the most aggressive type of skin cancer with an increasing rate in the last decades. Plant nano extracts such as nanopropolis are recommended for cancer treatment with fewer side effects and better effects. Liposomes containing plant compounds have been widely considered as targeted drug delivery systems in cancer treatment.
Shima Bidabad +4 more
wiley +1 more source
Expression and role of Bcl-xL in human hepatocellular carcinomas [PDF]
, 2001 Tetsuo Takehara +4 more
openalex +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.I recommend using Figure Graphical abstracts for the graphical table of contents and publication cover. This figure effectively illustrates probiotics LCs have therapeutic effects in a rat model of 5FU‐induced diarrhea, making it a compelling visual summary of our research.
Sheau‐Chung Tang +7 more
wiley +1 more source