Effect of 8 weeks high-intensity interval training (HIIT) with and without caloric restriction on gene expression of myocardial Bax and Bcl2 in mice [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2021 Background: Apoptosis is the physiological cell death that in natural conditions leads to the elimination of old, damaged, waste, and harmful cells. The aim of this study was the effect of eight weeks of high-intensity interval training (HIIT) with and ...
Mohammadreza Zarali +3 more
doaj +1 more source
Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution [PDF]
Journal of Pathology and Translational Medicine, 2021 Background Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia.
Meejeong Kim +7 more
doaj +1 more source
Renoprotective Potential of the Ultra-Pure Lipopolysaccharide from Rhodobacter Sphaeroides on Acutely Injured Kidneys in an Animal Model [PDF]
Archives of Razi Institute, 2021 One of the main causes of acute kidney injury is ischemic reperfusion injury (IRI). Inflammatory response, apoptotic damages, and oxidative stress-related injuries are all involved in the pathogenesis of IRI.
Munaf Aal-Aaboda +2 more
doaj +1 more source
Viral Bcl2s’ transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis [PDF]
Nature Communications, 2020 AbstractViral control of programmed cell death relies in part on the expression of viral analogs of the B-cell lymphoma 2 (Bcl2) protein known as viral Bcl2s (vBcl2s). vBcl2s control apoptosis by interacting with host pro- and anti-apoptotic members of the Bcl2 family.
Maria Jesús García-Murria +6 more
openaire +6 more sources
Effect of N-acetyl cysteine on oxidative stress and Bax and Bcl2 expression in the kidney tissue of rats exposed to lead [PDF]
The Ukrainian Biochemical Journal, 2021 This study aimed to consider the lead-induced oxidative damage of the kidney of male rats and the role of antioxidant N-acetylcysteine (NAC) in preserving cells against Pb toxicity.
M. Gholami +4 more
doaj +1 more source
The Incomplete Puzzle of the BCL2 Proteins [PDF]
Cells, 2019 The proteins of the BCL2 family are key players in multiple cellular processes, chief amongst them being the regulation of mitochondrial integrity and apoptotic cell death. These proteins establish an intricate interaction network that expands both the cytosol and the surface of organelles to dictate the cell fate.
Hector Flores-Romero +1 more
openaire +4 more sources
Biomedical Papers, 2021 Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
doaj +1 more source
BCL2 and MCL1 inhibitors for hematologic malignancies [PDF]
Blood, 2021 AbstractBCL2 and MCL1 are commonly expressed prosurvival (antiapoptotic) proteins in hematologic cancers and play important roles in their biology either through dysregulation or by virtue of intrinsic importance to the cell-of-origin of the malignancy. A new class of small-molecule anticancer drugs, BH3 mimetics, now enable specific targeting of these
Andrew H. Wei +4 more
openaire +3 more sources
Expression of Apoptosis Related and Proliferative Proteins in Malignant Lympho-Proliferative Disorders [PDF]
Iranian Journal of Pathology, 2017 Background & objective: The current study aimed to perform an immunohistochemical analysis of patterns of apoptotic and cell proliferative related protein expression in different histological grades and immune phenotypes of malignant lymphomas and other ...
Zeeba Jairajpuri +4 more
doaj +1 more source
Solitary Fibrous Tumour of the Clavicle: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2016 A Solitary Fibrous Tumour (SFT) is the preferred term by most of the pathologists than “haemangiopericytoma”. SFT is a heterogeneous group of benign and malignant neoplasms along a morphologic continuum. Here we report a case of SFT of the clavicle in a
Dileep Krishnamoorty Srinivas +4 more
doaj +1 more source