Results 181 to 190 of about 91,646 (261)

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Neuregulin 4‐dependent MAPK amplification mediates urate‐induced β‐cell dysfunction

open access: yesJournal of Diabetes Investigation, EarlyView.
Hyperuricemia impairs glucose homeostasis by inducing pancreatic β‐cell apoptosis without insulin resistance. In male Uox‐KO mice, urate upregulates Nrg4, which amplifies MAPK signaling and drives β‐cell death. Thus, hyperuricemia disrupts glucose metabolism via the Nrg4‐MAPK axis.
Yunyang Wang   +7 more
wiley   +1 more source

Prognostic Value of Bcl‐xL in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta‐Analysis

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma is a heterogeneous disease with poor survival outcomes. Bcl‐xL regulates tumor cell survival and apoptosis and has been associated with metastasis and poor prognosis, although its overall role remains undeciphered.
L. Leinonen   +6 more
wiley   +1 more source

Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective

open access: yesPeriodontology 2000, EarlyView.
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh   +3 more
wiley   +1 more source

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