Bakuchiol: From structural mimicry to systems‐level skin biology
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley +1 more source
The B-cell Receptor Blueprint in Lymphoma: Mechanisms and Therapeutic Opportunities. [PDF]
Casola S, Varano G.
europepmc +1 more source
BCL2-associated X protein (BAX); BCL2-antagonist/killer 1 (BAK1; BAK); B cell lymphoma 2 (BCL-2; BCL2); BCL2 homology domain 3 (BH3) [PDF]
openaire +1 more source
Neuregulin 4‐dependent MAPK amplification mediates urate‐induced β‐cell dysfunction
Hyperuricemia impairs glucose homeostasis by inducing pancreatic β‐cell apoptosis without insulin resistance. In male Uox‐KO mice, urate upregulates Nrg4, which amplifies MAPK signaling and drives β‐cell death. Thus, hyperuricemia disrupts glucose metabolism via the Nrg4‐MAPK axis.
Yunyang Wang +7 more
wiley +1 more source
Candida albicans hyphae modulate Staphylococcus aureus cell-free supernatant during dual biofilm growth to drive molecular signatures of oral dysplasia. [PDF]
Marin-Dett FH +6 more
europepmc +1 more source
BCL2-associated X protein (BAX); BCL2-antagonist/killer 1 (BAK1) [PDF]
openaire +1 more source
ABSTRACT Background Head and neck squamous cell carcinoma is a heterogeneous disease with poor survival outcomes. Bcl‐xL regulates tumor cell survival and apoptosis and has been associated with metastasis and poor prognosis, although its overall role remains undeciphered.
L. Leinonen +6 more
wiley +1 more source
Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh +3 more
wiley +1 more source
Capicua mediates interleukin-2 withdrawal-induced death of activated CD8<sup>+</sup> T cells. [PDF]
Shi JG +5 more
europepmc +1 more source

