Results 201 to 210 of about 150,149 (335)

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

open access: yesCancer Science, EarlyView.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa   +7 more
wiley   +1 more source

Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues

open access: yesCell Proliferation, EarlyView.
H1N1 infection during pregnancy specifically targets the fetal liver and lungs, triggering immune responses, tissue fibrosis and ferroptosis in parenchymal cells, ultimately leading to adverse pregnancy outcomes, offering insights into managing maternal H1N1 infections and their impact on fetal health.
Yuxi Jiang   +11 more
wiley   +1 more source

Venetoclax induces mitochondrial apoptosis and autophagy to overcome arsenic trioxide resistance in acute promyelocytic leukemia. [PDF]

open access: yesJ Transl Med
Dutta D   +18 more
europepmc   +1 more source

Frontline Therapy in Diffuse Large B‐Cell Lymphoma: Evolving Standards, Biological Insights, and Future Directions

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) remains the most common aggressive lymphoma, representing a biologically heterogeneous disease with diverse clinical behaviors. For more than two decades, R‐CHOP has been the cornerstone of frontline treatment, curing approximately two‐thirds of patients.
Mamdouh Skafi   +12 more
wiley   +1 more source

Immunohistochemical Expression of BCl2 Oncoprotein in Varying Histological Grades of Oral Squamous Cell Carcinoma

open access: yesOnline Journal of Health & Allied Sciences
Oral cancer has been rising in alarming numbers in the world which is anticipated to escalate at 70% by 2030. Although a lot of factors are responsible for the disease, genetics, and gene mutations play a major role in uncontrolled proliferation. Another
Subhalakshmi V   +3 more
doaj  

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