Results 241 to 250 of about 134,892 (289)

Perspectives on the interpretation of mitochondrial responses during skeletal muscle disuse‐induced atrophy

The Journal of Physiology, EarlyView.
Abstract figure legend Common human and rodent muscle disuse models and associated changes in skeletal muscle mitochondrial function; respiration, redox stress and apoptotic cell death. I–V, complexes I–V; ETF, electron transfer flavoprotein; Q, Q cycle; C, cytochrome c; Pi, inorganic phosphate; ROS, reactive oxygen species.
Luca J. Delfinis, Shahrzad Khajehzadehshoushtar, Christopher G. R. Perry   +2 more
wiley   +1 more source

Comprehensive Analysis of 177Lu-lilotomab Satetraxetan in Lymphoma Cell Lines: Implications for Precision Radioimmunotherapy and Combination Schemes

Patzke S, Cascione L, Melhus KB, Munz N, Arribas AJ, Gaudio E, Generalov R, Repetto-Llamazares AH, Dahle J, Bertoni F.   +9 more
europepmc   +1 more source

Inhibition of platin-induced BCL2 increase overcomes chemoresistance in squamous cell carcinoma of the head and neck through resensitization to cell death. [PDF]

Transl Oncol
Becker AS, Klauk F, Freitag T, Strüder DF, Schneider B, Zimpfer A, Maletzki C.   +6 more
europepmc   +1 more source

Five Cellular Genes as Candidates for Cervical Adenocarcinoma Molecular Markers. [PDF]

Cancers (Basel)
García-Montoya IA, López-Córdova KB, Marrero-Rodríguez D, Salcedo-Vargas M, Vargas-Requena CL, Escárcega-Avila AM, Martel-Estrada SA, Jiménez-Vega F.   +7 more
europepmc   +1 more source

Exosomes, autophagy, and cancer: A complex triad

International Journal of Cancer, Volume 157, Issue 3, Page 405-415, 1 August 2025.
Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés, Álvaro F. Fernández, Tania Fontanil   +2 more
wiley   +1 more source

Unveiling vitamin C: A new hope in the treatment of diffuse large B‑cell lymphoma (Review). [PDF]

Int J Oncol
Ren C, Li Y, Li M, Wang Y.
europepmc   +1 more source

TNF signature in advanced melanoma patients treated with immune checkpoint inhibitors: Results from the MELANFα clinical study

International Journal of Cancer, Volume 157, Issue 3, Page 534-548, 1 August 2025.
What's new? Tumor necrosis factor (TNF) can promote tumor resistance to immune checkpoint inhibitors (ICIs), which are now the standard treatment for advanced melanoma patients. Here, in an advanced melanoma patient cohort, TNF was investigated for a possible predictive relationship with ICI response. Assessments show that after 12 weeks of ICI therapy,
Mathieu Virazels, Amélie Lusque, Stéphanie Brayer, Matthieu Genais, Carine Dufau, Jean Milhès, Thomas Filleron, Cécile Pagès, Vincent Sibaud, Laurent Mortier, Olivier Dereure, Maha Ayyoub, Amandine Fabre, Nathalie Andrieu‐Abadie, Vera Pancaldi, Céline Colacios, Nicolas Meyer, Bruno Ségui, Anne Montfort   +18 more
wiley   +1 more source

Glycerol Supplementation During Oestrus Synchronisation With Fluorogestone Acetate Affects Follicular Proliferation, Maturation and Apoptosis of Granulosa Cells in Pelibuey Ewes. [PDF]

Reprod Domest Anim
Escorcia Ortiz P, Price CA, Guzmán Sánchez A, Guerrero-Netro HM.   +3 more
europepmc   +1 more source

TP53‐Mutated Acute Myeloid Leukemia: Unanswered Questions

Hematological Oncology, Volume 43, Issue 4, July 2025.
ABSTRACT TP53‐mutated acute myeloid leukemia (AML) remains one of the most treatment‐resistant hematologic malignancies, with poor overall survival despite advancements in therapeutic strategies. The loss of functional p53 compromises DNA repair, apoptosis, and genomic stability, rendering both conventional and novel therapies largely ineffective. This
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Caterina Labanca, Giulio Caridà, Francesco Mendicino, Eugenio Lucia, Virginia Olivito, Noemi Puccio, Antonino Neri, Fortunato Morabito, Massimo Gentile   +11 more
wiley   +1 more source

A New Class of BRCA1 Mimetics for ERα-Positive Breast Cancer Therapy: Design, Synthesis, In Silico Screening, In Vitro Assay, and Gene Expression Analysis. [PDF]

Life (Basel)
Shyam Sundar P, Selvaraj J, Alagarsamy V, Solomon VR, Natarajan J.   +4 more
europepmc   +1 more source