Results 131 to 140 of about 22,830 (227)

Highlights of 2025: advances in germinal centers

Immunology &Cell Biology, Volume 104, Issue 6, Page 609-612, July 2026.
Graphical summary of research advances made in 2025 in germinal center (GC) biology. GCB, germinal center B cells; Tfh, T follicular helper cell; APC, antigen‐presenting cell; FDC, follicular dendritic cell; SHM, somatic hypermutation. Created in BioRender. Webb, L. (2026) https://BioRender.com/bn9jx9v.
Louise MC Webb, Michelle A Linterman
wiley   +1 more source

t(3;6)(q27;p21) SFRS3/BCL6 [PDF]

, 2010
Review on t(3;6)(q27;p21) SFRS3/BCL6, with data on clinics, and the genes ...
Huret, JL, JL Huret
core   +1 more source

Hypoxic stress caused apoptosis of MDBK cells by p53/BCL6-mitochondrial apoptosis pathway

Animal Biotechnology
Hypoxia is an important characteristic of Tibetan plateau environment. It can lead to apoptosis, but the mechanism of apoptosis caused by hypoxic stress needs further clarification. Here, cattle kidney cell MDBK were used as cell model.
Bin Li, Yangjin Baima, Ji De, Dongxu Wen, Yang Liu, Zhuzha Basang, Nan Jiang   +6 more
doaj   +1 more source

Multiomics Profiling During Autoimmune Demyelination Highlights a Complex Regulatory Role for Ataxin‐1 in B Cells

Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.
Ataxin‐1 has been recently implicated in B cell regulation in the context of multiple sclerosis pathology. In this study, we used a multiomics pipeline to profile the B cell transcriptome, epigenome, and proteome in response to encephalitogenic challenges.
Jonathan J. Carver, Rachael R. Denbrock, Kristy M. Lau, Tonya N. Zeczycki, Changhong Yin, Weihua Huang, Alessandro Didonna   +6 more
wiley   +1 more source

Pharmaceutical inhibition of BCL6 ameliorates resistance to imatinib in chronic myeloid leukemia

Heliyon
The tyrosine kinase inhibitors (TKIs) have improved overall survival of CML (chronic myeloid leukemia) patients and allow them to experience normal life expectancy. However, relapse and drug resistance remain the main challenges in the clinical treatment
Yingying Xiao, Fang Deng, Yun Luo, Teng Wang   +3 more
doaj   +1 more source

Evaluation of Immunohistochemical Expression of C-MYC, BCL2, and BCL6 in High Grade B-cell Lymphoma [PDF]

Al-Anbar Medical Journal
Background: High-grade B-cell lymphoma (HGBCL) is characterized by chromosomal rearrangements involving specific oncogenes. The most commonly identified oncogenes in B-cell lymphomas are MYC, BCL2, and BCL6.
raghad hanna, zahraa Al-omar, mustafa Kachachi   +2 more
doaj   +1 more source

BCL6 modulation of acute lymphoblastic leukemia response to chemotherapy [PDF]

, 2016
The bone marrow niche has a significant impact on acute lymphoblastic leukemia (ALL) cell phenotype. Of clinical relevance is the frequency with which quiescent leukemic cells, in this niche, survive treatment and contribute to relapse.
Evans, R, Slone, W L, Hare, I, Moses, B S   +3 more
core   +1 more source

t(3;7)(q27;q32) FRA7H/BCL6 [PDF]

, 2013
Review on t(3;7)(q27;q32) FRA7H/BCL6, with data on clinics, and the genes ...
Huret, JL
core   +1 more source

BCL6 promotes the progression of high-grade serous ovarian cancer cells by inhibiting PLAAT4

Frontiers in Pharmacology
BackgroundB-cell lymphoma 6 (BCL6) is increasingly recognized as a driver of cancer progression; however, the precise molecular mechanisms by which BCL6 facilitates high-grade serous ovarian cancer (HGSOC) progression remain incompletely understood ...
An Wan, An Wan, An Wan, Wei-Dong Zhao, Gang Chen, Cheng Peng, Jin-Hui Tao, Jin-Hui Tao   +7 more
doaj   +1 more source

Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis [PDF]

Skeletal muscle is dynamically controlled by the balance of protein synthesis and degradation. Here we discover an unexpected function for the transcriptional repressor B cell lymphoma 6 (BCL6) in muscle proteostasis and strength in mice. Skeletal muscle-
Bederman, Ilya R., Demonbreun, Alexis R., Futtner, Christopher R., Waldeck, Nathan J., Barish, Grant D., Sommars, Meredith A., Quattrocelli, Mattia, McNally, Elizabeth M., Lai, Nicola, Wang, Janice C., Senagolage, Madhavi D., Prendergast, Erin, Fruzyna, Ellen, Telles, Carmen G., Omura, Yasuhiro, Ramachandran, Krithika, Arango, Daniel   +16 more
core   +1 more source