Results 121 to 130 of about 35,489 (280)
Respirology Case Reports, Volume 14, Issue 5, May 2026.An 81‐year‐old man presented with multiple bilateral pulmonary nodules and detection of Mycobacterium intracellulare, initially suggesting nontuberculous mycobacterial lung disease. However, heterogeneous radiological changes and progressive enlargement of selected nodules led to surgical lung biopsy, which revealed diffuse large B‐cell lymphoma with ...
Kosuke Masuda +13 more
wiley +1 more source
BCL6 promotes the progression of high-grade serous ovarian cancer cells by inhibiting PLAAT4
Frontiers in PharmacologyBackgroundB-cell lymphoma 6 (BCL6) is increasingly recognized as a driver of cancer progression; however, the precise molecular mechanisms by which BCL6 facilitates high-grade serous ovarian cancer (HGSOC) progression remain incompletely understood ...
An Wan +7 more
doaj +1 more source
Evaluation of Immunohistochemical Expression of C-MYC, BCL2, and BCL6 in High Grade B-cell Lymphoma [PDF]
Al-Anbar Medical JournalBackground: High-grade B-cell lymphoma (HGBCL) is characterized by chromosomal rearrangements involving specific oncogenes. The most commonly identified oncogenes in B-cell lymphomas are MYC, BCL2, and BCL6.
raghad hanna +2 more
doaj +1 more source
Analysis of Bcl6 in a genetically tractable human B cell line
, 2010 B cell lymphoma 6 (Bcl6) is a proto-oncogene functioning as a transcriptional repressor at the germinal centre (GC) stage of B cell development, regulating proliferation, differentiation and survival.
Zobel, Jennifer, Zobel, Jennifer
core +1 more source
British Journal of Haematology, Volume 208, Issue 5, Page 1535-1550, May 2026.Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu +3 more
wiley +1 more source
Prognostic Significance of Concurrent MYC, BCL2 and/or BCL6 Expression in Diffuse Large B-Cell Lymphoma [PDF]
, 2019 Masaki Gouda, MOHAMMED ABD ELMONEM
openalex +1 more source
ZBTB5 enhances the resistance of cervical cancer to paclitaxel by regulating BCL6 [PDF]
, 2023 Yue He +9 more
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Ambivalent role of BCL6 in cell survival and transformation [PDF]
Oncogene, 2003 The BCL6 gene is often structurally altered and probably 'misregulated' in two different types of human B-cell non-Hodgkin lymphomas (BNHL) thought to arise from germinal centre B cells. BCL6 encodes a BTB/POZ and zinc finger protein whose biochemical properties support a role as a DNA-binding transcriptional repressor and disclose, in part, the ...
openaire +2 more sources
European Journal of Haematology, Volume 116, Issue 5, Page 522-534, May 2026.ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) remains the most common aggressive lymphoma, representing a biologically heterogeneous disease with diverse clinical behaviors. For more than two decades, R‐CHOP has been the cornerstone of frontline treatment, curing approximately two‐thirds of patients.
Mamdouh Skafi +12 more
wiley +1 more source
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT Lymphoid structures (LS) arising in nonlymphoid tissues are increasingly recognized as active immune niches rather than simple consequences of chronic inflammation. In this review, we propose a framework that distinguishes inflammatory lymphoid structures (ILS) from mature tertiary lymphoid structures (mTLS), while acknowledging that these ...
Marie Frutoso +6 more
wiley +1 more source