Results 111 to 120 of about 22,830 (227)

Single‐Nucleus Multiomic Analysis Reveals Immune–Metabolic Reprogramming Consistent With Maladaptive Trained Immunity in HIV‐Associated Neurocognitive Disorders

open access: yesGlia, Volume 74, Issue 8, August 2026.
Single‐nucleus multiomic profiling of postmortem brain reveals coordinated immune, metabolic, and epigenomic reprogramming in glia of people with HIV consistent with maladaptive trained immunity sustaining neuroinflammation in HAND. ABSTRACT HIV‐associated neurocognitive disorders (HAND) remain prevalent in people with HIV (PWH) despite effective ...
Siera Martinez   +8 more
wiley   +1 more source

A Rare Case of Cutaneous Crystal‐Storing Histiocytosis With Kappa Light Chain Restriction and Unusual BCL6 Expression

open access: yesJournal of Cutaneous Pathology, Volume 53, Issue 8, Page 682-686, August 2026.
ABSTRACT Crystal‐storing histiocytosis (CSH) is a rare histopathologic phenomenon characterized by the accumulation of crystalline material within histiocytes, most often associated with lymphoplasmacytic or plasma cell neoplasms. Cutaneous involvement is uncommon and may present diagnostic challenges.
Liangli Wang   +8 more
wiley   +1 more source

Drug Research in Inhibiting BCL6 in Ovarian Cancer [PDF]

open access: yes, 2023
Ovarian cancer has a survival rate of 50 percent just five years after being diagnosed (Nguyen et al. 2020). Finding new ways to treat ovarian cancer is important to increase the survival of patients who have been diagnosed.
Beek, Quinn E, Walker, Sarah
core   +1 more source

BCL6 is expressed in glioblastoma tumors and cell lines. [PDF]

open access: yes, 2020
A. Proportion of BCL6+ cells in 62 human GBM tumors (top), and representative IHC staining of 2 of 62 human GBM tumors, highlighting heterogeneous BCL6 protein (brown staining). B. BCL6+ GBM tumors after stratification by IDH1 mutation (top) p53 mutation
Melanie J. McConnell (4413490)   +12 more
core   +1 more source

Role of the Transcriptional Repressor BCL6 in Allergic Response and Inflammation

open access: yesWorld Allergy Organization Journal, 2008
Various molecules participate in different phases of allergic reactions. This means that many genes are encoding molecules related to allergic reactions, such as cytokines, chemokines, and their receptors as effector molecules.
Masafumi Arima   +2 more
doaj   +1 more source

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 384-395, August 2026.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking   +6 more
wiley   +1 more source

BCL6 (B-Cell Lymphoma 6) [PDF]

open access: yes, 2007
Review on BCL6 (B-Cell Lymphoma 6), with data on DNA, on the protein encoded, and where the gene is ...
Knezevich, S
core   +1 more source

An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation.

open access: yesPLoS Pathogens, 2017
The latent EBV nuclear antigen 3C (EBNA3C) is required for transformation of primary human B lymphocytes. Most mature B-cell malignancies originate from malignant transformation of germinal center (GC) B-cells.
Yonggang Pei   +4 more
doaj   +1 more source

Prognostic impact of diffuse large B-cell lymphoma with extra copies of MYC, BCL2 and/or BCL6: comparison with double/triple hit lymphoma and double expressor lymphoma

open access: yesDiagnostic Pathology, 2019
Background The poor outcome of high-grade B-cell lymphoma, with rearrangements of MYC, BCL2 and/or BCL6, also known as double-hit lymphoma or triple-hit lymphoma (DHL or THL), has been well documented, while the clinical significance of extra copies of ...
Sixia Huang   +9 more
doaj   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1393-1402, July 2026.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Home - About - Disclaimer - Privacy