Results 101 to 110 of about 22,830 (227)

Minimal residual disease in diffuse large B‐cell lymphoma after first‐line therapy: Defining the continuum from metabolic remission to molecular clearance

British Journal of Haematology, EarlyView.
Summary Response assessment in diffuse large B‐cell lymphoma (DLBCL) has traditionally relied on anatomical and metabolic imaging, with fluorodeoxyglucose positron emission tomography (FDG‐PET)–defined complete metabolic remission representing the principal end‐point of first‐line therapy. However, growing evidence indicates that metabolic control does
Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Mamdouh Skafi, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

The Bcl6-SMRT/NCoR Cistrome Represses Inflammation to Attenuate Atherosclerosis [PDF]

, 2012
SummaryChronic inflammation is a hallmark of atherosclerosis, but its transcriptional underpinnings are poorly understood. We show that the transcriptional repressor Bcl6 is an anti-inflammatory regulator whose loss in bone marrow of Ldlr−/− mice results
Barish, Grant D., Yu, Ruth T., Evans, Ronald M., Cerchietti, Leandro, Diehl, Cody, Tseng, Tiffany W., Tangirala, Rajendra K., Becerra, Diana, Tai, Li-Jung, Kim, Jason, Karunasiri, Malith S., LeBlanc, Matthias, Witztum, Joseph L., Melnick, Ari M., Dent, Alexander L., Miller, Yury I.   +15 more
core   +1 more source

B-Cell Lymphoma 6 (BCL6) Is a Host Restriction Factor That Can Suppress HBV Gene Expression and Modulate Immune Responses

Frontiers in Microbiology, 2019
Hepatitis B virus (HBV) infection causes acute and chronic liver inflammation. Recent studies have demonstrated that some viral antigens can suppress host innate and adaptive immunity, and thus lead to HBV liver persistency. However, the cellular factors
Chun-Ta Lin, Chun-Ta Lin, Yue-Ting Hsieh, Yeng-Jey Yang, Shih-Hui Chen, Cheng-Hsuan Wu, Lih-Hwa Hwang   +6 more
doaj   +1 more source

Comparative effectiveness of chimeric antigen receptor (CAR) T‐cell therapy versus historical controls in patients with relapse/refractory aggressive B‐cell lymphoma: An indirect treatment comparison in the real‐world setting

British Journal of Haematology, EarlyView.
Summary Single‐arm studies demonstrate dramatic improvements in survival in patients with relapsed/refractory (R/R) aggressive B‐cell lymphomas but with significant toxicities and at exceptionally high costs. The objective of this study was to evaluate the real‐world health outcomes of aggressive B‐cell lymphoma patients treated with publicly funded ...
Pierre J. A. Villeneuve, Lee Mozessohn, Nibene H. Somé, Rebecca E. Mercer, Lisa Masucci, Tom Kouroukis, Chris Bredeson, Suriya Aktar, Qi Guan, Anca Prica, Christine I. Chen, Danielle Rodin, Matthew Cheung, Munaza Chaudhry, Scott Gavura, Cassandra McKay, William W. L. Wong, Kelvin K. W. Chan   +17 more
wiley   +1 more source

BCL6 is a target of miR-205. [PDF]

, 2012
A: Effect of the analysed miRNAs on the empty vector. Cells co-transfected with the miRNA expression vectors, vector control and the empty reporter vector ware tested in luciferase assays.
Anne Dueck (145404), Julia Alles (145377), Jochen Imig (121364), Christoph Renner (24366), Friedrich A. Grässer (145412), Tanja Reineke (145392), Stephanie Barth (145387), Jiayun Zhu (145382), Marianne Tinguely (145395), Sergio Cogliatti (145399), Gunter Meister (47028), Natalie Motsch (145375)   +11 more
core   +1 more source

BCL6-SPECC1L: A Novel Fusion Gene in Nasopharyngeal Carcinoma

Technology in Cancer Research & Treatment, 2022
Background: Nasopharyngeal carcinomas (NPCs) are malignant tumors originating from the lining epithelium of the nasopharynx. Fusion genes have been confirmed to play important roles in the occurrence and development of various malignant tumors, but the ...
Shuo-Gui Fang PhD, Tian-Liang Xia PhD, Jian-Chang Fu MBBS, Tong Li MSc, Qian Zhong PhD, Fei Han PhD   +5 more
doaj   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Role of BCL6 oncogene in B-cell lymphomas [PDF]

, 2017
BCL6 es un represor transcripcional indispensable para la inmunidad adaptativa, dado que es esencial para la formación del centro germinal, donde se produce la generación de anticuerpos de alta afinidad.
Iglesias Montalvo, Carmen
core  

BCL6 (B-Cell Lymphoma 6) [PDF]

, 2013
Review on BCL6 (B-Cell Lymphoma 6), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL
core   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source