Results 101 to 110 of about 35,489 (280)
Diagnostic Pathology, 2019 Background The poor outcome of high-grade B-cell lymphoma, with rearrangements of MYC, BCL2 and/or BCL6, also known as double-hit lymphoma or triple-hit lymphoma (DHL or THL), has been well documented, while the clinical significance of extra copies of ...
Sixia Huang +9 more
doaj +1 more source
The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]
, 2018 The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni +3 more
core +1 more source
Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor [PDF]
, 2023 Ahmed Mamai +36 more
openalex +1 more source
Glia, Volume 74, Issue 6, June 2026.Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma +6 more
wiley +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
MedComm – Oncology, Volume 5, Issue 2, June 2026.Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
The 3D Genome Browser: A web-based browser for visualizing 3D genome organization and long-range chromatin interactions [PDF]
, 2018 Here, we introduce the 3D Genome Browser, http://3dgenome.org, which allows users to conveniently explore both their own and over 300 publicly available chromatin interaction data of different types.
Choudhary, Mayank N.K. +12 more
core +2 more sources
European Journal of Haematology, Volume 116, Issue 6, Page 771-784, June 2026.ABSTRACT Primary refractory Diffuse Large B‐Cell Lymphoma is associated with poor outcomes and limited responsiveness to conventional salvage therapies. Although CAR T‐cell therapy represents the standard of care in this setting, a substantial proportion of patients cannot receive it despite meeting disease‐related criteria. In this review, “unsuitable”
Santino Caserta +12 more
wiley +1 more source
Histopathology, Volume 88, Issue 7, Page 1324-1347, June 2026.Diffuse large B‐cell lymphoma/high‐grade B‐cell lymphoma (DLBCL/HGBCL) is a mature aggressive B‐cell lymphoma. This article performed a comprehensive clinicopathological and transcriptomic analyses of this lymphoma category. Aims Diffuse large B‐cell lymphoma/high‐grade B‐cell lymphoma (DLBCL/HGBCL) with MYC and BCL2 rearrangements (double‐hit lymphoma
Masashi Miyaoka +21 more
wiley +1 more source
TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases. [PDF]
, 2019 CD4+ Foxp3+ T regulatory (Treg) cells are key players in preventing lethal autoimmunity. Tregs undertake differentiation processes and acquire diverse functional properties.
Cho, Sunglim +12 more
core +1 more source
An Oncogenic Role for Alternative NF-κB Signaling in DLBCL Revealed upon Deregulated BCL6 Expression [PDF]
, 2009 SummaryDiffuse large B cell lymphoma (DLBCL) is a complex disease comprising diverse subtypes and genetic profiles. Possibly because of the prevalence of genetic alterations activating canonical NF-κB activity, a role for oncogenic lesions that activate ...
Alizadeh +48 more
core +3 more sources